Treatment of oromandibular dystonia with botulinum toxin A improves apnea in a teenager with quadriplegic cerebral palsy: A case report.

Journal of pediatric rehabilitation medicine 2024 Vol.17(1) p. 125-129

Roberts J, Tenaglia A, Bellissimo E, Kim H

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Abstract

This report describes a 15-year-old female with known spastic and dystonic quadriplegic cerebral palsy (CP), Gross Motor Function Classification System IV, and obstructive sleep apnea (OSA). She experienced decreased apneic episodes after receiving onabotulinumtoxin A (BoNT-A) injections for the treatment of oromandibular dystonia (OMD). After her OSA diagnosis, she initially received injections to the bilateral masseter and temporalis muscles with no effect on the frequency of nightly apneic episodes. Subsequently, the bilateral lateral pterygoid muscles were added and she was later noted to have fewer apneic episodes overnight. This case report describes the use of BoNT-A in the muscles of mastication for management of OMD and the ensuing improvement in OSA in a teenager with CP.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 1
시술 onabotulinumtoxin 보툴리눔독소 주사 dict 1
해부 cerebral scispacy 1
해부 temporalis muscles scispacy 1
해부 muscles scispacy 1
약물 botulinum toxin A C0006050
botulinum toxin type A
scispacy 1
약물 onabotulinumtoxin A scispacy 1
질환 oromandibular dystonia C2242577
Oromandibular dystonia
scispacy 1
질환 apnea C0003578
Apnea
scispacy 1
질환 quadriplegic cerebral palsy C0393995
Quadriplegic cerebral palsy
scispacy 1
질환 spastic C0443306
Spastic
scispacy 1
질환 cerebral palsy C0007789
Cerebral Palsy
scispacy 1
질환 obstructive sleep apnea C0520679
Sleep Apnea, Obstructive
scispacy 1
질환 OSA → obstructive sleep apnea C0520679
Sleep Apnea, Obstructive
scispacy 1
기타 female scispacy 1
기타 BoNT-A scispacy 1
기타 bilateral lateral pterygoid muscles scispacy 1

MeSH Terms

Female; Adolescent; Humans; Botulinum Toxins, Type A; Dystonia; Cerebral Palsy; Neuromuscular Agents; Dystonic Disorders; Sleep Apnea, Obstructive

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