Botulinum Toxin A Injection for Treatment of Chronic Skin Ulcer: A Case Series and Literature Review.
Abstract
Chronic skin ulcer (CSU) often combines with a variety of refractory factors that respond poorly to routine treatments. Botulinum toxin A (BTX-A) can be injected subcutaneously to improve the local blood supply, to reduce pain, and to promote wound healing. At present, few reports have mentioned BTX-A injection for chronic skin ulcer treatment. We observed the effect of four cases that used BTX-A to treat CSU and provided a brief review of the literature. Four cases of CSUs with 4 different causes were treated with BTX-A injection (4 U/cm). The specific operation is as follows: local, multipoint, cyclic, equidistant, and subcutaneous injections with a depth of 6 to 8 mm. The ulcer area was significantly reduced. Subsequently, the ulcer healed within 20 to 48 days. Botulinum toxin A is recommended as an important treatment for chronic skin ulcer that can improve healing of skin ulcers with various etiologies.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | botulinum toxin
|
보툴리눔독소 주사 | dict | 3 | |
| 해부 | subcutaneous
|
피하조직 | dict | 1 |
MeSH Terms
Adolescent; Adult; Aged; Botulinum Toxins, Type A; Chronic Disease; Female; Follow-Up Studies; Humans; Injections, Intralesional; Injections, Subcutaneous; Male; Middle Aged; Patient Safety; Risk Assessment; Sampling Studies; Severity of Illness Index; Skin Ulcer; Wound Healing
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