Effect of Botulinum Toxin on Disabling Neuropathic Pain: A Case Presentation Suggesting a New Therapeutic Strategy.

PM & R : the journal of injury, function, and rehabilitation 2017 Vol.9(2) p. 200-203

Buonocore M, Demartini L, Mandrini S, Dall'Angelo A, Dalla Toffola E

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Abstract

[UNLABELLED] This case presentation describes a 47-year-old woman who developed complex regional pain syndrome type II with severe neuropathic pain following iatrogenic transection of the tibial nerve at the ankle. The pain and disability progressively worsened over time, markedly impaired ambulation, and were not relieved despite various analgesic treatments. After injection of botulinum toxin (abobotulinumtoxinA, BoNT-A) in the leg muscles the tendons of which pass through the tarsal tunnel (together with the tibial nerve), her pain decreased and her walking capacity improved. This case suggests a new therapeutic role for botulin toxin in treating peripheral neuropathic pain caused by movement-evoked ectopic potentials.

[LEVEL OF EVIDENCE] V.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 2

MeSH Terms

Acetylcholine Release Inhibitors; Ankle Joint; Botulinum Toxins, Type A; Female; Humans; Iatrogenic Disease; Middle Aged; Neuralgia; Pain Management; Pain Measurement

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