Double Chin Correction with Combination of High Intensity Focused Ultrasound and Hyaluronic Acid: A 24-Week Case Report.

Submental fullness, commonly referred to as a double chin, is a frequent aesthetic concern influenced by subcutaneous fat accumulation and underlying skeletal structure. High-intensity focused ultrasound (HIFU) and hyaluronic acid (HA) filler injection have each been used as minimally invasive treatment options; however, reports on their combined use remain limited. We report two Asian female patients with mild to moderate submental fullness who were treated with a sequential combination of linear HIFU and HA filler injection in routine clinical practice. One patient underwent HIFU followed by HA injection, whereas the other received HA injection prior to HIFU treatment. Both patients demonstrated improvement in submental contour, cervicomental angle, and chin projection during follow-up, with results maintained at 24 weeks. Patient satisfaction was high, treatment-related discomfort was minimal, and no immediate or delayed adverse events were observed. Although limited by the small number of cases, these observations suggest that a combined approach using HIFU and HA filler may represent a well-tolerated, minimally invasive option for selected patients with submental fullness.