Upfront radiation for small, nongrowing vestibular schwannomas: a call for caution.

Neurosurgical review 2025 Vol.49(1) p. 18

Andresen NS, Macielak RJ, Schoo DP, Ren Y, Wu KC, Prevedello DM, Adunka OF, Saunders WH

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Abstract

The management of small vestibular schwannomas (VS) with serviceable hearing remains controversial. While stereotactic radiosurgery (SRS) achieves high tumor control rates, its routine use for nongrowing, asymptomatic tumors may represent overtreatment. Decades of natural history data demonstrate that more than half of small or intracanalicular VSs remain radiographically stable for 10 years or longer, and many patients report high satisfaction with observation. Although SRS offers short-term hearing preservation, long-term outcomes show progressive decline, with fewer than half of patients maintaining serviceable hearing at five years and even fewer beyond a decade. Radiation also introduces potential late toxicities and complicates subsequent microsurgical salvage. Observation, by contrast, defers unnecessary intervention while preserving future treatment options and quality of life. For small, stable VSs, evidence supports a "wait-and-scan" strategy as the safest, most patient-centered initial management approach, reserving SRS or microsurgery for documented tumor progression or symptomatic deterioration.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 microsurgery 미세수술 dict 1

MeSH Terms

Humans; Neuroma, Acoustic; Radiosurgery; Treatment Outcome; Quality of Life; Microsurgery

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