Free Flap Surgery and Oncologic Care of the Pregnant Head and Neck Cancer Patient.

Head & neck 2025 Vol.47(6) p. 1788-1801

Chen S, Ramirez RJ, Khan MN, Urken ML, Sifri Y, Berkin JA, Roof SA

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Abstract

[BACKGROUND] Although head and neck cancer (HNC) in pregnant patients is rare, the incidence of oral cavity cancer has increased in younger women of childbearing age. We detail the complexities of two cases of HNC during pregnancy requiring surgical resection with free flap reconstruction, followed by general guidelines for HNC care of this population.

[METHODS] We report two cases of head and neck cancer management in the pregnant patient.

[RESULTS] Both patients underwent similar free flap reconstruction for oral cavity cancer. One was able to avoid adjuvant and deliver a healthy child at term, while the second required early termination followed by chemotherapy and radiation. Both remain disease free.

[CONCLUSIONS] Multidisciplinary management is crucial in care for the pregnant HNC patient. Goals include cumulative radiation dose exposures below 100 mGy, operating in the second trimester when the risk is lowest to the fetus and mother, and avoiding chemotherapy or radiation in the first trimester when possible.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 free flap 피판재건술 dict 3
해부 Flap scispacy 1
해부 fetus scispacy 1
합병증 oral cavity cancer scispacy 1
합병증 oral cavity scispacy 1
약물 HNC → head and neck cancer C0278996
Malignant Head and Neck Neoplasm
scispacy 1
약물 [CONCLUSIONS] Multidisciplinary scispacy 1
질환 Cancer C0006826
Malignant Neoplasms
scispacy 1
질환 head and neck cancer C0278996
Malignant Head and Neck Neoplasm
scispacy 1
질환 HNC → head and neck cancer C0278996
Malignant Head and Neck Neoplasm
scispacy 1
질환 Head and Neck Cancer Patient scispacy 1
기타 women scispacy 1

MeSH Terms

Humans; Female; Pregnancy; Free Tissue Flaps; Pregnancy Complications, Neoplastic; Adult; Head and Neck Neoplasms; Plastic Surgery Procedures; Carcinoma, Squamous Cell; Mouth Neoplasms

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