Low Skeletal Muscle Mass: A Strong Predictive Factor for Surgical Complications After Free Forearm Flap Reconstruction in Oral Cancer Patients.

Head & neck 2025 Vol.47(4) p. 1135-1141

Ansari E, Minulina NC, van Beers MA, van Es RJJ, Dieleman FJ, Rosenberg AJWP, Janssen LM, Braunius WW, Van Cann EM, de Bree R

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Abstract

[BACKGROUND] Low skeletal muscle mass (SMM) is a predictive factor for complications in patients undergoing major head and neck cancer surgery. This study aims to identify the predictive value of low SMM for postoperative complications in patients who underwent free forearm flap (FAFF) reconstructions after oral cancer resections.

[METHODS] A retrospective study was performed with all patients who underwent FFAF between 2003 and 2020 for an oral cavity reconstruction after cancer ablation. Free flap related, any postoperative complications and hospital stay were investigated.

[RESULTS] Low SMM was associated with an increased risk of free flap associated complications (OR 2.14; 95% CI 1.02-4.39, p = 0.029). Low SMM was associated with severe complications (Clavien-Dindo ≥ III) (OR 1.46; 95% CI 1.20-2.09, p = 0.02).

[CONCLUSIONS] Low SMM is a strong predictive factor for free flap related surgical complications in patients undergoing FAFF reconstruction after resection of oral cancer.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 free flap 피판재건술 dict 3
시술 flap 피판재건술 dict 2
해부 Low Skeletal Muscle Mass scispacy 1
합병증 Forearm Flap scispacy 1
합병증 oral cavity scispacy 1
약물 SMM → skeletal muscle mass C5554793
Skeletal Muscle Mass
scispacy 1
약물 [BACKGROUND] Low scispacy 1
약물 [RESULTS] Low SMM scispacy 1
약물 CI 1.02 scispacy 1
약물 [CONCLUSIONS] Low SMM scispacy 1
질환 Skeletal Muscle C0242692
Skeletal muscle structure
scispacy 1
질환 Cancer C0006826
Malignant Neoplasms
scispacy 1
질환 Low skeletal muscle mass C5554793
Skeletal Muscle Mass
scispacy 1
질환 head and neck cancer C0278996
Malignant Head and Neck Neoplasm
scispacy 1
질환 oral cancer C0153381
Malignant neoplasm of mouth
scispacy 1
질환 Oral Cancer Patients scispacy 1
질환 SMM → skeletal muscle mass scispacy 1
기타 patients scispacy 1
기타 FFAF scispacy 1

MeSH Terms

Humans; Mouth Neoplasms; Male; Female; Retrospective Studies; Free Tissue Flaps; Middle Aged; Postoperative Complications; Forearm; Plastic Surgery Procedures; Aged; Muscle, Skeletal; Adult; Risk Factors

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