[Prophylactic breast surgery: The role of DIEP (Deep Inferior Epigastric)].

Bulletin du cancer 2025 Vol.112(3) p. 300-306

Michot A, Adam D, Fournier M, Charitansky H, Auriol S, Vinel A, Burnier P, Commeny J, Dannepond A

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Abstract

In France, breast cancer is the most common cancer among women, with 5 to 10% of cases being genetic. Frequently involved genes include BRCA1 and BRCA2, PALB2, TP53, CDH1, and PTEN, among others. Approximately, two in 1000 women carry a BRCA1 or BRCA2 gene mutation. The National Cancer Institute (INCa) provides guidelines for screening and risk-reduction treatments. Prophylactic surgery, including bilateral mastectomy, is a preventive option for high-risk women. Immediate breast reconstruction (IBR), particularly using the DIEP flap technique, helps mitigate the psychological impact of mastectomy, and is part of the gold standard to be offered to patients. This technique uses excess of skin and fat from the lower abdomen and requires micro-surgical skills. Despite logistical challenges, this method is favored for its durability and natural outcome. INCa and other organizations are working to improve access and information for these treatments.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 breast 유방 dict 3
시술 diep flap 피판재건술 dict 1
해부 skin scispacy 1
해부 fat scispacy 1
합병증 DIEP ( scispacy 1
합병증 bilateral mastectomy scispacy 1
합병증 abdomen scispacy 1
질환 DIEP C0082274
diclofenac epolamine
scispacy 1
질환 breast cancer C0006142
Malignant neoplasm of breast
scispacy 1
질환 cancer C0006826
Malignant Neoplasms
scispacy 1
질환 PALB2 C1744034
PALB2 protein, human
scispacy 1
기타 women scispacy 1
기타 BRCA1 scispacy 1
기타 BRCA2 scispacy 1
기타 PALB2 scispacy 1
기타 TP53 scispacy 1
기타 CDH1 scispacy 1
기타 PTEN scispacy 1
기타 IBR → Immediate breast reconstruction scispacy 1
기타 patients scispacy 1

MeSH Terms

Prophylactic Mastectomy; France; Breast Neoplasms; Genetic Predisposition to Disease; Mammaplasty; Microsurgery; Epigastric Arteries; Perforator Flap; Humans; Female; Abdominal Muscles; Subcutaneous Fat, Abdominal; Treatment Outcome

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