Bivalirudin for unsalvageable venous congestion or obstruction in head and neck free flap reconstruction.
Abstract
Microvascular free flap surgery permits single-stage reconstruction of complex head and neck ablative defects. Venous congestion can occur in the early postoperative period, risking partial or total flap loss. While prompt surgical re-exploration is often required, a number of adjunct medical treatments have been explored. Recently, there has been an anecdotal rise in the use of the anticoagulant bivalirudin, a recombinant derivative of hirudin. However, there has only been one case series report on the use of bivalirudin in head and neck free flap venous congestion. Here, we describe our team's experience with bivalirudin through a series of 7 patients.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | free flap
|
피판재건술 | dict | 3 | |
| 시술 | microvascular
|
미세수술 | dict | 1 | |
| 시술 | flap
|
피판재건술 | dict | 1 | |
| 약물 | Bivalirudin
|
C0168273
bivalirudin
|
scispacy | 1 | |
| 약물 | hirudin
|
C0019573
hirudin
|
scispacy | 1 | |
| 질환 | unsalvageable venous congestion or obstruction in head and neck free flap reconstruction
|
scispacy | 1 | ||
| 질환 | Venous congestion
|
C0042484
Venous Engorgement
|
scispacy | 1 | |
| 질환 | head and neck free flap
|
scispacy | 1 | ||
| 질환 | head and neck
|
scispacy | 1 | ||
| 질환 | head and neck free flap venous
|
scispacy | 1 | ||
| 기타 | venous
|
scispacy | 1 |
MeSH Terms
Humans; Recombinant Proteins; Hirudins; Male; Peptide Fragments; Head and Neck Neoplasms; Free Tissue Flaps; Middle Aged; Plastic Surgery Procedures; Female; Aged; Hyperemia; Antithrombins
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