Efficacy analysis of minimally invasive surgery for Raynaud's syndrome.

BMC surgery 2023 Vol.23(1) p. 313

Yu F, Liu Y, Zhang C, Pang B, Zhang D, Zhao W, Li X, Yang W

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Abstract

[BACKGROUND] Raynaud's syndrome (RS), also referred to as Raynaud's phenomenon, is a vasospastic disorder causing episodic color changes in extremities upon exposure to cold or stress. These manifestations, either primary Raynaud's phenomenon (PRP) or associated with connective tissue diseases like systemic sclerosis (SSc) as secondary Raynaud's phenomenon (SRP), affect the quality of life. Current treatments range from calcium channel blockers to innovative surgical interventions, with evolving efficacy and safety profiles.

[METHODS] In this retrospective study, patients diagnosed with RS were selected based on complete medical records, ensuring homogeneity between groups. Surgeries involved microscopic excision of sympathetic nerve fibers and stripping of the digital artery's adventitia. Postoperative care included antibiotics, analgesia, oral nifedipine, and heat therapies. Evaluation metrics such as the VAS pain score and RCS score were collected bi-weekly. Data analysis was conducted using SPSS 26.0, with significance set at p < 0.05.

[RESULTS] In total, 15 patients formed the experimental group, with five presenting fingertip soft tissue necrosis and ten showing RS symptoms. Comparative analysis of demographic data between experimental and control groups, both containing 15 participants, demonstrated no significant age and gender difference. However, the "Mean Duration of RP attack" in the experimental group was notably shorter (9.47 min ± 0.31) than the control group (19.33 min ± 1.79). The RS Severity Score also indicated milder severity for the experimental cohort (score: 8.55) compared to the control (score: 11.23). Postoperative assessments at 2, 4, and 6 weeks revealed improved VAS pain scores, RCS scores, and other measures for the experimental group, showing significant differences (p < 0.05). One distinctive case showcased a variation in the common digital nerve and artery course in an RS patient.

[CONCLUSION] Our retrospective analysis on RS patients indicates that microsurgical techniques are safe and effective in the short term. As surgical practices lean towards minimally invasive methods, our data supports this shift. However, extensive, prospective studies are essential for conclusive insights.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 connective tissue scispacy 1
해부 adventitia scispacy 1
해부 oral scispacy 1
합병증 tissue necrosis 괴사 dict 1
합병증 extremities scispacy 1
합병증 fingertip soft scispacy 1
약물 PRP → primary Raynaud's phenomenon C0151445
Primary Raynaud Phenomenon
scispacy 1
약물 calcium C0006675
calcium
scispacy 1
약물 nifedipine C0028066
nifedipine
scispacy 1
약물 ± 0.31) scispacy 1
약물 [BACKGROUND] scispacy 1
약물 [RESULTS] scispacy 1
질환 Raynaud's syndrome C0034735
Raynaud Phenomenon
scispacy 1
질환 Raynaud's phenomenon C0034735
Raynaud Phenomenon
scispacy 1
질환 vasospastic disorder scispacy 1
질환 primary Raynaud scispacy 1
질환 connective tissue diseases like systemic sclerosis scispacy 1
질환 SSc → systemic sclerosis C0036421
Systemic Scleroderma
scispacy 1
질환 pain C0030193
Pain
scispacy 1
질환 presenting fingertip soft scispacy 1
질환 necrosis C0027540
Necrosis
scispacy 1
질환 RCS scispacy 1
기타 PRP → primary Raynaud's phenomenon scispacy 1
기타 patients scispacy 1
기타 artery scispacy 1
기타 patient scispacy 1

MeSH Terms

Humans; Retrospective Studies; Quality of Life; Prospective Studies; Raynaud Disease; Minimally Invasive Surgical Procedures; Pain

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