Outcomes of KTP Laser Ablation in Glottic Neoplasms: A Systematic Review and Meta-Analysis.
Abstract
[OBJECTIVES] To evaluate the safety and clinical effectiveness of transoral laser microsurgery (TLM) with potassium-titanyl-phosphate (KTP) laser ablation for glottic neoplasms.
[DATA SOURCE] MEDLINE via PubMed, SCOPUS, Web of Science, and Cochrane Library.
[REVIEW METHODS] A systematic review and meta-analysis of studies assessing the safety and efficacy of KTP laser therapy in patients with early-stage glottic neoplasms.
[RESULTS] Eight studies were included. After an average follow-up of 3.3 years, the overall survival and disease-free survival for patients who underwent KTP were 90.7% (95% CI 85%-96.5%) and 98.5% (95% CI 97.3%-99.8%), respectively. In the single-arm meta-analysis, the pooled estimate of recurrence was 7.7% (95% CI 3.4%-12%). The overall voice handicap index (VHI) estimate attributed to KTP in the single-arm meta-analysis was 6.76 (95% CI [3.05, 10.48]) and 5.21 (95% CI [2.86, 7.56]) within 6 months and after a one-year follow-up, respectively.
[CONCLUSION] KTP laser ablation is a safe and effective method for treating patients with early glottic neoplasms. Laryngoscope, 133:1806-1814, 2023.
[DATA SOURCE] MEDLINE via PubMed, SCOPUS, Web of Science, and Cochrane Library.
[REVIEW METHODS] A systematic review and meta-analysis of studies assessing the safety and efficacy of KTP laser therapy in patients with early-stage glottic neoplasms.
[RESULTS] Eight studies were included. After an average follow-up of 3.3 years, the overall survival and disease-free survival for patients who underwent KTP were 90.7% (95% CI 85%-96.5%) and 98.5% (95% CI 97.3%-99.8%), respectively. In the single-arm meta-analysis, the pooled estimate of recurrence was 7.7% (95% CI 3.4%-12%). The overall voice handicap index (VHI) estimate attributed to KTP in the single-arm meta-analysis was 6.76 (95% CI [3.05, 10.48]) and 5.21 (95% CI [2.86, 7.56]) within 6 months and after a one-year follow-up, respectively.
[CONCLUSION] KTP laser ablation is a safe and effective method for treating patients with early glottic neoplasms. Laryngoscope, 133:1806-1814, 2023.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | microsurgery
|
미세수술 | dict | 1 | |
| 약물 | potassium-titanyl-phosphate
|
scispacy | 1 | ||
| 약물 | [OBJECTIVES]
|
scispacy | 1 | ||
| 약물 | [DATA SOURCE] MEDLINE
|
scispacy | 1 | ||
| 약물 | SCOPUS
|
scispacy | 1 | ||
| 약물 | CI [
|
scispacy | 1 | ||
| 질환 | neoplasms
|
C0027651
Neoplasms
|
scispacy | 1 | |
| 질환 | early-stage glottic neoplasms
|
scispacy | 1 | ||
| 질환 | Glottic Neoplasms: A
|
scispacy | 1 | ||
| 질환 | glottic neoplasms
|
scispacy | 1 | ||
| 기타 | patients
|
scispacy | 1 |
MeSH Terms
Humans; Glottis; Laryngeal Neoplasms; Voice Quality; Laser Therapy; Treatment Outcome; Microsurgery; Tongue Neoplasms; Retrospective Studies
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