Spinal Dural Arteriovenous Fistulas: A Retrospective Analysis of Prognostic Factors and Long-Term Clinical Outcomes in the Light of the Recent Diagnostic and Technical Refinements.
Abstract
Spinal dural arteriovenous fistulas (dAVFs) are abnormal connections between the meningeal branches of segmental arteries and a radiculomedullary veins that result in a progressive myelopathy thanks to perimedullary coronal venous plexus congestion. Usually, dAVFs show nonspecific symptoms, thus leading to late clinical suspicion and a difficult MRI diagnosis.Several authors have tried to identify prognostic factors before treatment, but published studies results are often inconsistent and sometimes contradictory.In this study, we reviewed our recent experience of 30 dAVF patients where we collected all demographic, clinical and angioarchitectural features as well as radiological and treatment-related characteristics. The thoracic spine was the most common location, constituting 53.3% of cases, followed by the lumbar roots, comprising 30%. About 83% of patients showed motor deficits, urinary disturbances were present in 70%, and bowel symptoms in 50%.We treated 86.7% of patients with microsurgery and 13.3% with endovascular occlusion with a mean interval between clinical onset and intervention of 10.8 ± 14.2 months.A significant clinical improvement was observed at follow-up in 80% of patients, with a significant reduction in mean G-score, U-score and F-score at a mean follow-up of 105.89 ± 191.9 months.However, none among the principal demographic, clinical and radiological characteristics showed significant prognostic value to the clinical improvement observed at follow-up.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | microsurgery
|
미세수술 | dict | 1 | |
| 해부 | bowel
|
scispacy | 1 | ||
| 해부 | endovascular
|
scispacy | 1 | ||
| 합병증 | meningeal branches
|
scispacy | 1 | ||
| 합병증 | thoracic spine
|
scispacy | 1 | ||
| 약물 | ± 191.9
|
scispacy | 1 | ||
| 약물 | Long-Term
|
scispacy | 1 | ||
| 약물 | urinary
|
scispacy | 1 | ||
| 질환 | Spinal dural arteriovenous fistulas
|
C0752156
Dural Arteriovenous Fistula
|
scispacy | 1 | |
| 질환 | myelopathy
|
C0005956
Bone Marrow Diseases
|
scispacy | 1 | |
| 질환 | endovascular occlusion
|
scispacy | 1 | ||
| 기타 | Dural Arteriovenous
|
scispacy | 1 | ||
| 기타 | arteries
|
scispacy | 1 | ||
| 기타 | veins
|
scispacy | 1 | ||
| 기타 | patients
|
scispacy | 1 | ||
| 기타 | roots
|
scispacy | 1 |
MeSH Terms
Humans; Prognosis; Retrospective Studies; Central Nervous System Vascular Malformations; Spine; Spinal Cord Diseases
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