Transversus abdominus plane blocks do not reduce rates of postoperative prolonged opioid use following abdominally based autologous breast reconstruction: a nationwide longitudinal analysis.

European journal of plastic surgery 2023 Vol.46(2) p. 203-213

Chattopadhyay A, Shah JK, Yesantharao P, Ho VT, Sheckter CC, Nazerali R

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Abstract

[BACKGROUND] The transversus abdominus plane (TAP) block reduces postoperative donor site pain in patients undergoing autologous breast reconstruction with an abdominally based flap. This study aimed to determine the effect of TAP blocks on rates of conversion to chronic opioid use.

[METHODS] The Clinformatics Data Mart was queried from 2003 to 2019, extracting adult encounters for abdominally based free and pedicled flaps based on common procedural terminology (CPT) codes. Patients were excluded if they had filled a narcotic prescription 1 year to 30 days prior to surgery. The exposure variable-TAP block-was identified by CPT codes. Outcomes were evaluated using morphine milligram equivalents (MME) from prescriptions filled between 30 days prior to and 30 days after surgery. Chronic opioid use (COU) was defined as receiving 4 unique prescriptions or a 60-day supply between 30 and 180 days after surgery.

[RESULTS] Of the 4091 patients, (mean age 51.2 ± 9.0 years), 181 (4.4%) had a TAP block placed. Perioperative MMEs/day, postoperative COU, and length of stay did not differ in patients who received a TAP block (p = 0.142; p = 0.271). Significant predictors of risk of conversion to COU included younger age, pedicled abdominal flap, Elixhauser comorbidity index score > 3, filling a psychiatric medication prescription, and filling a benzodiazepine prescription.

[CONCLUSIONS] In patients undergoing autologous breast reconstruction with abdominally based flap reconstruction, TAP blocks do not decrease perioperative MME/day, conversion to chronic opioid use, or length of stay. These data suggest that intraoperative TAP block placement may be a low-yield opioid-reduction strategy.Level of evidence: Level III, risk/prognostic study.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 flap 피판재건술 dict 3
해부 breast 유방 dict 3
합병증 pedicled flaps scispacy 1
합병증 pedicled abdominal scispacy 1
약물 CPT → common procedural terminology scispacy 1
약물 morphine C0026549
morphine
scispacy 1
약물 COU → Chronic opioid use scispacy 1
약물 ± 9.0 scispacy 1
약물 benzodiazepine C0005064
Benzodiazepines
scispacy 1
약물 [BACKGROUND] The scispacy 1
약물 [CONCLUSIONS] In scispacy 1
질환 pain C0030193
Pain
scispacy 1
질환 comorbidity C0009488
Comorbidity
scispacy 1
질환 psychiatric C0033873
Psychiatry Specialty
scispacy 1
질환 MME → milligram equivalents scispacy 1
질환 COU → Chronic opioid use scispacy 1
기타 transversus abdominus scispacy 1
기타 TAP → transversus abdominus plane scispacy 1
기타 patients scispacy 1

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