Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia.
💡 한 문장 핵심
폐경 후 안드로겐성 탈모 여성에서 finasteride의 효능 부재.
4/5 보강
TL;DR
In postmenopausal women with AGA, finasteride 1 mg/day taken for 12 months did not not increase hair growth or slow the progression of hair thinning.
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
추출되지 않음
I · Intervention 중재 / 시술
finasteride 1 mg/day or placebo
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Finasteride was generally well tolerated. [CONCLUSION] In postmenopausal women with AGA, finasteride 1 mg/day taken for 12 months did not not increase hair growth or slow the progression of hair thinning.
📑 코퍼스 인용 관계
· 인용됨 43
📑 인용한 논문 (6) ▾
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연도별 인용 (2012–2026) · 합계 166
OpenAlex 토픽 ·
Hair Growth and Disorders
Ovarian function and disorders
Facial Rejuvenation and Surgery Techniques
Abstract 🌐 Abstract
[BACKGROUND] Finasteride, an inhibitor of type 2 5alpha-reductase, decreases serum and scalp dihydrotestosterone (DHT) by inhibiting conversion of testosterone to DHT and has been shown to be effective in men with androgenetic alopecia (AGA). The effects of finasteride in women with AGA have not been evaluated.
[OBJECTIVE] The purpose of this study was to evaluate the efficacy of finasteride in postmenopausal women with AGA.
[METHODS] In this 1-year, double-blind, placebo-controlled, randomized, multicenter trial, 137 postmenopausal women (41-60 years of age) with AGA received finasteride 1 mg/day or placebo. Efficacy was evaluated by scalp hair counts, patient and investigator assessments, assessment of global photographs by a blinded expert panel, and histologic analysis of scalp biopsy specimens.
[RESULTS] After 1 year of therapy, there was no significant difference in the change in hair count between the finasteride and placebo groups. Both treatment groups had significant decreases in hair count in the frontal/parietal (anterior/mid) scalp during the 1-year study period. Similarly, patient, investigator, and photographic assessments as well as scalp biopsy analysis did not demonstrate any improvement in slowing hair thinning, increasing hair growth, or improving the appearance of the hair in finasteride-treated subjects compared with the placebo group. Finasteride was generally well tolerated.
[CONCLUSION] In postmenopausal women with AGA, finasteride 1 mg/day taken for 12 months did not not increase hair growth or slow the progression of hair thinning.
[OBJECTIVE] The purpose of this study was to evaluate the efficacy of finasteride in postmenopausal women with AGA.
[METHODS] In this 1-year, double-blind, placebo-controlled, randomized, multicenter trial, 137 postmenopausal women (41-60 years of age) with AGA received finasteride 1 mg/day or placebo. Efficacy was evaluated by scalp hair counts, patient and investigator assessments, assessment of global photographs by a blinded expert panel, and histologic analysis of scalp biopsy specimens.
[RESULTS] After 1 year of therapy, there was no significant difference in the change in hair count between the finasteride and placebo groups. Both treatment groups had significant decreases in hair count in the frontal/parietal (anterior/mid) scalp during the 1-year study period. Similarly, patient, investigator, and photographic assessments as well as scalp biopsy analysis did not demonstrate any improvement in slowing hair thinning, increasing hair growth, or improving the appearance of the hair in finasteride-treated subjects compared with the placebo group. Finasteride was generally well tolerated.
[CONCLUSION] In postmenopausal women with AGA, finasteride 1 mg/day taken for 12 months did not not increase hair growth or slow the progression of hair thinning.
In postmenopausal women with AGA, finasteride 1 mg/day taken for 12 months did not not increase hair growth or slow the progression of hair thinning.
APA 7
Price, V. H., Roberts, J. L., Hordinsky, M., Olsen, E. A., Savin, R., Bergfeld, W., Fiedler, V., Lucky, A., Whiting, D. A., Pappas, F., Culbertson, J., Kotey, P., Meehan, A., & Waldstreicher, J. (2000). Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia.. Journal of the American Academy of Dermatology, 43(5 Pt 1), 768-76. https://doi.org/10.1067/mjd.2000.107953
Vancouver
Price VH, Roberts JL, Hordinsky M, Olsen EA, Savin R, Bergfeld W, et al. Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia. Jour. Amer. Acad. Derm.. 2000;43(5 Pt 1):768-76. doi:10.1067/mjd.2000.107953
AMA 11
Price VH, Roberts JL, Hordinsky M, Olsen EA, Savin R, Bergfeld W, et al. Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia. Jour. Amer. Acad. Derm.. 2000;43(5 Pt 1):768-76. doi:10.1067/mjd.2000.107953
Chicago
Price, V. H., Roberts, J. L., Hordinsky, M., Olsen, E. A., Savin, R., Bergfeld, W., Fiedler, V., Lucky, A., Whiting, D. A., Pappas, F., and .... 2000. "Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia." Journal of the American Academy of Dermatology 43 (5 Pt 1): 768-76. https://doi.org/10.1067/mjd.2000.107953
MLA 9
Price, V. H., et al. "Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia." Journal of the American Academy of Dermatology, vol. 43, no. 5 Pt 1, 2000, pp. 768-76. doi:10.1067/mjd.2000.107953.
PMID
11050579 ↗
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
인용 관계
그래프 OA 노드: 7/8 (88%)
· 참조 0편 · 후속 7편
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