Pyoderma gangrenosum after deep inferior epigastric perforator flap: How prompt diagnosis and treatment can avoid surgical debridement and further morbidity.

JPRAS open 2022 Vol.33() p. 42-46

Bombardelli J, Parikh J, Morkuzu S, Spiegel AJ

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Abstract

Pyoderma gangrenosum (PG) is a skin disorder characterized by painful, enlarging necrotic ulcers with bluish borders surrounded by advancing zones of erythema. The key histologic feature is neutrophilic infiltration of the superficial and deep layers of the dermis and the absence of microorganisms. Although rare and associated with autoimmune diseases such as rheumatoid arthritis, ulcerative colitis and Crohn's disease, the diagnosis is commonly missed at presentation and patients are often treated for infection with antibiotics and surgical debridement. We present a case of PG in a 51 year-old woman after a deep inferior epigastric perforator (DIEP) flap for breast reconstruction who was promptly diagnosed and treated with steroids with appropriate response. Our case highlights the importance of rapid diagnosis and treatment of this disease to avoid incorrect management including surgical debridement, which can exacerbate the disease and increase its morbidity.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 flap 피판재건술 dict 2
해부 breast 유방 dict 1
해부 skin scispacy 1
해부 dermis scispacy 1
합병증 infection 감염 dict 1
합병증 Pyoderma scispacy 1
합병증 necrotic ulcers scispacy 1
합병증 erythema scispacy 1
합병증 ulcerative colitis scispacy 1
약물 steroids C0038317
Steroids
scispacy 1
질환 Pyoderma gangrenosum C0085652
Pyoderma Gangrenosum
scispacy 1
질환 skin disorder C0037274
Dermatologic disorders
scispacy 1
질환 necrotic ulcers scispacy 1
질환 erythema C0041834
Erythema
scispacy 1
질환 autoimmune diseases C0004364
Autoimmune Diseases
scispacy 1
질환 rheumatoid arthritis C0003873
Rheumatoid Arthritis
scispacy 1
질환 ulcerative colitis C0009324
Ulcerative Colitis
scispacy 1
질환 Crohn's disease C0010346
Crohn Disease
scispacy 1
질환 Crohn scispacy 1
질환 disease scispacy 1
기타 patients scispacy 1

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