Pain management with popliteal block for fibular graft harvesting in head and neck reconstruction; a randomised double-blind placebo-controlled study.

Oral oncology 2022 Vol.128() p. 105833

Persson K, Sjövall J, Kander T, Walther-Sturesson L

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Abstract

[BACKGROUND AND OBJECTIVES] Curative treatment for locally advanced head and neck tumours often includes reconstructive surgery using a microvascular free flap. Effective recuperation is essential but may be impeded by postoperative donor site pain. The aim of this study was to evaluate the effects of a continuous popliteal block on postoperative pain after fibular graft harvesting.

[MATERIAL AND METHODS] In this randomized double-blind placebo-controlled study adult patients scheduled for reconstructive head and neck surgery with a microvascular free fibular graft received an indwelling popliteal nerve block catheter and were randomized to receive continuous levobupivacaine/ropivacaine or placebo during the first postoperative week. Primary outcome was postoperative extremity pain assessed using the numerated rating scale (NRS). Secondary outcomes included opioid consumption.

[RESULTS] In total 24 patients were included. The median (median, IQR [range]) postoperative extremity NRS scores was lower in the local anaesthetic (LA) group (2, 0-3 [0-10]) compared to the placebo group (2, 1-4 [0-10]), p = 0.008. The LA group also experienced fewer episodes of breakthrough pain, defined as NRS ≥ 4 (17% vs 33% of observations), p = 0.009. Furthermore, median (median, IQR [range]) opioid consumption the first postoperative week was lower in the LA group (109 mg, 74-134 [19-611]) compared to the placebo group (202 mg, 135-241 [78-749]), p = 0.010. No complications attributed to the blocks were observed.

[CONCLUSION] Continuous popliteal block significantly reduced postoperative extremity pain and opioid consumption in patients undergoing fibular graft harvesting for head and neck reconstructive surgery.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 microvascular 미세수술 dict 2
시술 free flap 피판재건술 dict 1
해부 fibular graft scispacy 1
합병증 flap scispacy 1
약물 levobupivacaine/ropivacaine C0873118
levobupivacaine
scispacy 1
약물 [BACKGROUND AND OBJECTIVES] scispacy 1
약물 [MATERIAL AND scispacy 1
약물 opioid scispacy 1
질환 Pain C0030193
Pain
scispacy 1
질환 popliteal block scispacy 1
질환 head and neck tumours C0018671
Head and Neck Neoplasms
scispacy 1
질환 postoperative pain C0030201
Pain, Postoperative
scispacy 1
질환 head and neck surgery C1512343
Head and Neck Surgery
scispacy 1
질환 postoperative extremity pain scispacy 1
질환 NRS → numerated rating scale scispacy 1
질환 significantly reduced postoperative extremity scispacy 1
질환 head and neck reconstructive scispacy 1
질환 head and neck scispacy 1
기타 popliteal scispacy 1
기타 patients scispacy 1
기타 popliteal nerve scispacy 1

MeSH Terms

Adult; Analgesics, Opioid; Anesthetics, Local; Double-Blind Method; Humans; Pain Management; Pain Measurement; Postoperative Pain; Ropivacaine

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