Giant Pituitary Adenoma - Special Considerations.

Otolaryngologic clinics of North America 2022 Vol.55(2) p. 351-379

Tang OY, Hsueh WD, Eloy JA, Liu JK

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Abstract

Giant pituitary adenomas (GPAs) comprise 5% to 15% of pituitary adenomas, but have higher rates of extrasellar invasion, subtotal resection, surgical morbidity, and recurrence. With the possible exception of giant prolactinomas, GPAs require surgical decompression. On review of 3 decades of case series encompassing 699 microsurgical transsphenoidal (MT), 1060 endoscopic endonasal trans-sphenoidal (EET), and 513 transcranial (TC) patients, gross total resection and recurrence rates were comparable across modalities, but the EET approach had lower perioperative mortality and superior restoration of visual function. Each approach has unique indications. Combined EET-TC approaches for minimizing residual tumor represent another area of study.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
합병증 extrasellar scispacy 1
약물 EET → endoscopic endonasal trans-sphenoidal scispacy 1
기법 endoscopic 내시경 dict 1
질환 Pituitary Adenoma C0032000
Pituitary Adenoma
scispacy 1
질환 Giant pituitary adenomas C0032000
Pituitary Adenoma
scispacy 1
질환 pituitary adenomas C0032000
Pituitary Adenoma
scispacy 1
질환 prolactinomas C0033375
Prolactinoma
scispacy 1
질환 EET-TC scispacy 1
질환 tumor C0027651
Neoplasms
scispacy 1
기타 patients scispacy 1

MeSH Terms

Adenoma; Endoscopy; Humans; Pituitary Neoplasms; Retrospective Studies; Treatment Outcome

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