Salvage surgery for residual or recurrent laryngeal squamous cell carcinoma after (Chemo)radiotherapy: Oncological outcomes and prognostic factors.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2021 Vol.47(11) p. 2711-2721

Vander Poorten V, Meulemans J, Beitler JJ, Piazza C, Kowalski LP, Mäkitie AA, Paleri V, Rinaldo A, Robbins KT, Rodrigo JP, Silver CE, Sjögren EV, Strojan P, Takes RP, Ferlito A

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Abstract

Nonsurgical primary treatment of early and advanced laryngeal squamous cell carcinoma, employing radiotherapy with or without chemotherapy, is considered a standard of care in many centers throughout the world. When patients have persistent or recurrent disease after non-surgical treatment, salvage surgery is frequently the only remaining potentially curative treatment. Depending on the extent of the residual/recurrent disease, different surgical salvage options are at the surgeon's disposal. In selected cases with limited local disease, salvage transoral laser microsurgery, transoral robotic surgery and open partial laryngectomies can be employed to achieve cure while preserving laryngeal function. For more advanced cases total laryngectomy is necessary. Identifying situations with unacceptable results from surgical salvage may guide future therapies.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 microsurgery 미세수술 dict 1
해부 laryngectomies scispacy 1
해부 laryngeal scispacy 1
기법 robotic surgery 로봇수술 dict 1
질환 squamous cell carcinoma C0007137
Squamous cell carcinoma
scispacy 1
질환 laryngeal squamous cell carcinoma scispacy 1
기타 patients scispacy 1

MeSH Terms

Carcinoma, Squamous Cell; Chemoradiotherapy; Humans; Laryngeal Neoplasms; Laryngectomy; Laser Therapy; Microsurgery; Neoplasm Recurrence, Local; Neoplasm, Residual; Prognosis; Robotic Surgical Procedures; Salvage Therapy

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