Voice Quality After Radiotherapy and Cordectomy in Early-Stage Glottic Carcinomas.

Ear, nose, & throat journal 2021 Vol.100(4) p. NP173-NP176

Mehel DM, Özgür A, Şahin N, Vural AA, Yemiş T, Çelebi M, Aydemir S, Özdemir D, Akgül G

Abstract

Laryngeal carcinomas are the most common upper respiratory tract cancers and most commonly involve the glottic region. The aim of this study is to evaluate the voice quality after radiotherapy (RT) and microsurgical cordectomy (MC) treatments using Voice Handicap Index (VHI) and Grade, Roughness, Breathiness, Astenicity, and Strain (GRBAS) perceptual evaluation scale in patients with early-stage glottic carcinoma. A total of 37 patients with early-stage glottic carcinomas, 19 patients had RT and 18 patients with MC, were included in our study. The patients were evaluated in terms of their sound quality by using VHI-10 and GRBAS perceptual assessment scale 3 months after the treatment was completed. Although the findings were better in favor of RT according to GRBAS perceptual assessment scale of patients who received RT (n = 19) and MC (n = 18), no statistically significant difference was found between the 2 groups ( = .613). Patients in both groups were evaluated with VHI-10, emotional ( = .036) and physiological ( = .038) scores were significantly higher in MC group and no significant difference was found in functional scores ( = .192). However, there was no statistically significant difference between the 2 groups in terms of voice quality ( = .185). In early-stage (Tis, T1a, T1b) glottic carcinoma, there was no significant difference between RT and MC in terms of voice quality. Therefore, the choice of treatment modality in patients with early-stage glottic carcinoma should be taken into account in terms of the patient's occupation, comorbid diseases, cost of treatment, hospital stay, and, most importantly, patient preference.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 glottic scispacy 1
질환 Glottic Carcinomas C0740083
Carcinoma of glottis
scispacy 1
질환 Laryngeal carcinomas C0595989
Carcinoma of larynx
scispacy 1
질환 upper respiratory tract cancers C0458578
Upper respiratory tract
scispacy 1
질환 early-stage glottic carcinoma scispacy 1
질환 early-stage glottic carcinomas scispacy 1
질환 glottic carcinoma C0740083
Carcinoma of glottis
scispacy 1
질환 comorbid diseases scispacy 1
질환 tract cancers scispacy 1
질환 early-stage scispacy 1
질환 Tis scispacy 1
질환 T1a scispacy 1
기타 patients scispacy 1
기타 patient scispacy 1

MeSH Terms

Adult; Aged; Carcinoma; Combined Modality Therapy; Female; Glottis; Humans; Laryngeal Neoplasms; Laryngectomy; Male; Microsurgery; Middle Aged; Neoplasm Staging; Postoperative Complications; Postoperative Period; Radiation Injuries; Radiotherapy; Retrospective Studies; Treatment Outcome; Vocal Cords; Voice Disorders; Voice Quality