Potential Patent Blue V Overdose in a Patient Undergoing Free-Flap Breast Reconstruction: A Case Report.
Abstract
The case of a patient who experienced serious adverse effects following a potential overdose of Patent Blue V dye (PVB) is presented here. A 65-year-old woman developed cardiac arrythmias and circulatory instability 35 minutes after receiving 100 mg PVB during breast cancer surgery. An allergic reaction was assumed and treated accordingly. Intraoperatively, both epinephrine and norepinephrine infusions were required to support circulation. However, mast-cell tryptase levels were normal and subsequent allergy testing for all potential allergens was negative. This case highlights that life-threatening reactions to perioperative PVB should not always be attributed to anaphylaxis; systemic toxicity could occur with an overdose.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 해부 | breast
|
유방 | dict | 2 | |
| 시술 | flap
|
피판재건술 | dict | 1 | |
| 해부 | cardiac
|
scispacy | 1 | ||
| 약물 | norepinephrine
|
C0028351
norepinephrine
|
scispacy | 1 | |
| 약물 | PVB
|
scispacy | 1 | ||
| 약물 | epinephrine
|
에피네프린 | dict | 1 | |
| 질환 | Overdose
|
C0029944
Drug Overdose
|
scispacy | 1 | |
| 질환 | cardiac arrythmias
|
scispacy | 1 | ||
| 질환 | breast cancer
|
C0006142
Malignant neoplasm of breast
|
scispacy | 1 | |
| 질환 | allergic reaction
|
C0020517
Hypersensitivity
|
scispacy | 1 | |
| 질환 | allergy
|
C0002111
Allergy Specialty
|
scispacy | 1 | |
| 질환 | anaphylaxis
|
C0002792
anaphylaxis
|
scispacy | 1 | |
| 질환 | toxicity
|
C0040539
Toxicity aspects
|
scispacy | 1 | |
| 질환 | PVB
|
scispacy | 1 | ||
| 기타 | Blue
|
scispacy | 1 | ||
| 기타 | Patient
|
scispacy | 1 | ||
| 기타 | Free-Flap
|
scispacy | 1 | ||
| 기타 | Blue V
|
scispacy | 1 | ||
| 기타 | mast-cell tryptase
|
scispacy | 1 |
MeSH Terms
Aged; Coloring Agents; Female; Humans; Mammaplasty; Rosaniline Dyes; Sentinel Lymph Node Biopsy
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