Comparison of the surgical outcomes of free flap reconstruction for primary and recurrent head and neck cancers: a case-controlled propensity score-matched study of 1,791 free flap reconstructions.

Scientific reports 2021 Vol.11(1) p. 2350

Chen KH, Kuo SCH, Chien PC, Hsieh HY, Hsieh CH

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Abstract

This study was designed to compare the outcome and analyze the operation-related risk factors in free flap reconstruction for patients with primary and recurrent head and neck cancers. A 1:1 propensity score-matched analysis of the microsurgery registry database of the hospital. The primary outcome of the free flap reconstruction had a higher failure rate in the recurrent group than the primary group (5.1% vs. 3.1%, p = 0.037). Among the 345 pairs in the matched study population, there were no significant differences between the primary and recurrent groups regarding the rate of total flap loss (3.5% vs. 5.5%, p = 0.27) and secondary outcomes. This study revealed that free flap reconstruction had a higher failure rate in the recurrent group than the primary group, but such a difference may be attributed by the different patient characteristics.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 free flap 피판재건술 dict 5
시술 microsurgery 미세수술 dict 1
시술 flap 피판재건술 dict 1
질환 head and neck cancers C0278996
Malignant Head and Neck Neoplasm
scispacy 1
기타 patients scispacy 1
기타 patient scispacy 1

MeSH Terms

Female; Free Tissue Flaps; Head and Neck Neoplasms; Humans; Male; Microsurgery; Middle Aged; Neoplasm Recurrence, Local; Propensity Score; Plastic Surgery Procedures; Retrospective Studies; Treatment Outcome

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