Seven Microaneurysms: Description of an Experimental Rodent Model for Neurovascular Training.

Turkish neurosurgery 2021 Vol.31(2) p. 217-222

Feijoo PG, Benito F, Kalra N, Cárdenas GP, Alegre MS, Sánchez CV, Domínguez VR, Frade J

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Abstract

[AIM] To demonstrate the microsurgical procedures, and to evaluate the feasibility of living models of experimental neurovascular training by developing new complex vascular exercises mimicking the most common intracranial aneurysms.

[MATERIAL AND METHODS] The procedures were performed under a Zeiss (OPMI pico f170) microscope using basic microsurgery instruments, 10/0 Nylon and blue Polypropylene micro-sutures. We selected adult albino Wistar rats weighing between 258 and 471g each. Seven different aneurysm types were created using carotid, jugular, cava, aorta and femoral vessels.

[RESULTS] Seven types of aneurysm were designed and created in the rat with a high-medium successful rate. There are differences in terms of realism and the difficulty of performance, according to the different types: lateral wall, bifurcation, top of the basilar, fusiform, fusiform + involved branch, Anterior Communicating Artery (ACoA) and giant. The steps and technical issues to produce these exercises are described.

[CONCLUSION] We show the feasibility of creating several types of aneurysm using different vessels in a rodent model. Training on these models help to improve microsurgical skills, allowing safe practice for neurosurgeons in all stages of their career.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 microsurgery 미세수술 dict 1
해부 carotid scispacy 1
해부 cava scispacy 1
해부 aorta scispacy 1
해부 basilar scispacy 1
해부 Anterior scispacy 1
해부 vessels scispacy 1
합병증 intracranial scispacy 1
합병증 aneurysm types scispacy 1
합병증 fusiform scispacy 1
합병증 aneurysm scispacy 1
약물 [MATERIAL AND scispacy 1
질환 Microaneurysms C0333101
Microaneurysm
scispacy 1
질환 intracranial aneurysms C0007766
Intracranial Aneurysm
scispacy 1
질환 aneurysm C0002940
Aneurysm
scispacy 1
질환 ACoA → Anterior Communicating Artery C0149562
Structure of anterior communicating artery
scispacy 1
기타 Neurovascular scispacy 1
기타 vascular scispacy 1
기타 albino Wistar rats scispacy 1
기타 jugular scispacy 1
기타 femoral vessels scispacy 1
기타 rat scispacy 1
기타 lateral wall scispacy 1

MeSH Terms

Animals; Anterior Cerebral Artery; Circle of Willis; Disease Models, Animal; Female; Humans; Intracranial Aneurysm; Microaneurysm; Microsurgery; Neurosurgical Procedures; Rats; Rats, Wistar; Rodentia; Vascular Surgical Procedures

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