Seven Microaneurysms: Description of an Experimental Rodent Model for Neurovascular Training.
Abstract
[AIM] To demonstrate the microsurgical procedures, and to evaluate the feasibility of living models of experimental neurovascular training by developing new complex vascular exercises mimicking the most common intracranial aneurysms.
[MATERIAL AND METHODS] The procedures were performed under a Zeiss (OPMI pico f170) microscope using basic microsurgery instruments, 10/0 Nylon and blue Polypropylene micro-sutures. We selected adult albino Wistar rats weighing between 258 and 471g each. Seven different aneurysm types were created using carotid, jugular, cava, aorta and femoral vessels.
[RESULTS] Seven types of aneurysm were designed and created in the rat with a high-medium successful rate. There are differences in terms of realism and the difficulty of performance, according to the different types: lateral wall, bifurcation, top of the basilar, fusiform, fusiform + involved branch, Anterior Communicating Artery (ACoA) and giant. The steps and technical issues to produce these exercises are described.
[CONCLUSION] We show the feasibility of creating several types of aneurysm using different vessels in a rodent model. Training on these models help to improve microsurgical skills, allowing safe practice for neurosurgeons in all stages of their career.
[MATERIAL AND METHODS] The procedures were performed under a Zeiss (OPMI pico f170) microscope using basic microsurgery instruments, 10/0 Nylon and blue Polypropylene micro-sutures. We selected adult albino Wistar rats weighing between 258 and 471g each. Seven different aneurysm types were created using carotid, jugular, cava, aorta and femoral vessels.
[RESULTS] Seven types of aneurysm were designed and created in the rat with a high-medium successful rate. There are differences in terms of realism and the difficulty of performance, according to the different types: lateral wall, bifurcation, top of the basilar, fusiform, fusiform + involved branch, Anterior Communicating Artery (ACoA) and giant. The steps and technical issues to produce these exercises are described.
[CONCLUSION] We show the feasibility of creating several types of aneurysm using different vessels in a rodent model. Training on these models help to improve microsurgical skills, allowing safe practice for neurosurgeons in all stages of their career.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | microsurgery
|
미세수술 | dict | 1 | |
| 해부 | carotid
|
scispacy | 1 | ||
| 해부 | cava
|
scispacy | 1 | ||
| 해부 | aorta
|
scispacy | 1 | ||
| 해부 | basilar
|
scispacy | 1 | ||
| 해부 | Anterior
|
scispacy | 1 | ||
| 해부 | vessels
|
scispacy | 1 | ||
| 합병증 | intracranial
|
scispacy | 1 | ||
| 합병증 | aneurysm types
|
scispacy | 1 | ||
| 합병증 | fusiform
|
scispacy | 1 | ||
| 합병증 | aneurysm
|
scispacy | 1 | ||
| 약물 | [MATERIAL AND
|
scispacy | 1 | ||
| 질환 | Microaneurysms
|
C0333101
Microaneurysm
|
scispacy | 1 | |
| 질환 | intracranial aneurysms
|
C0007766
Intracranial Aneurysm
|
scispacy | 1 | |
| 질환 | aneurysm
|
C0002940
Aneurysm
|
scispacy | 1 | |
| 질환 | ACoA
→ Anterior Communicating Artery
|
C0149562
Structure of anterior communicating artery
|
scispacy | 1 | |
| 기타 | Neurovascular
|
scispacy | 1 | ||
| 기타 | vascular
|
scispacy | 1 | ||
| 기타 | albino Wistar rats
|
scispacy | 1 | ||
| 기타 | jugular
|
scispacy | 1 | ||
| 기타 | femoral vessels
|
scispacy | 1 | ||
| 기타 | rat
|
scispacy | 1 | ||
| 기타 | lateral wall
|
scispacy | 1 |
MeSH Terms
Animals; Anterior Cerebral Artery; Circle of Willis; Disease Models, Animal; Female; Humans; Intracranial Aneurysm; Microaneurysm; Microsurgery; Neurosurgical Procedures; Rats; Rats, Wistar; Rodentia; Vascular Surgical Procedures
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