The successful use of a bespoke OssDsign cranial plate to reconstruct an occipital defect following excision of a recurrent epithelioid sarcoma.

JPRAS open 2020 Vol.24() p. 71-76

Bloom O, Goddard N, Yannoulias B, Eccles S

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Abstract

A cranioplasty has a number of known associated complications including infection for non-biological implants and bone flap resorption where autologous grafts are used. In recent years, bioactive ceramic cranial implants have been developed as a new reconstructive option. The OssDsign cranial plate (OssDsign AB, Uppsala, Sweden) was first introduced in 2010 and consists of an interconnected mosaic of hydroxyapatite tiles mounted onto a 3D-printed titanium mesh. Each tile is composed of a monetite, beta-calcium pyrophosphate, beta-tricalcium phosphate and brushite compound designed to mimic the process of coupled bone formation once implanted. This case presents a patient's journey from diagnosis of an epithelioid sarcoma over the posterior scalp and its management in the following 7 years. Initial excision of the lesion was reconstructed with a tissue expander and local rotational flap. Recurrence of the disease 3 years later was treated with a course of radical radiotherapy. Persistent osteomyelitis over the next 3 years resulted in chronic ulceration and exposed bone in the treated area. As the first part of a 3-stage treatment plan, two separate tissue expanders became infected. The multidisciplinary team therefore chose to use a bespoke OssDsign cranial plate combined with a deep inferior epigastric perforator (DIEP) free flap to provide a definitive single operative solution. The advantages over other reconstruction options include that the plate can be removed should further excision be required, greater potential for long-term integration with surrounding tissues and the ability to be soaked in antibiotic to reduce the risk of infection.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 flap 피판재건술 dict 2
합병증 infection 감염 dict 2
시술 free flap 피판재건술 dict 1
해부 grafts scispacy 1
해부 bone scispacy 1
해부 tissue scispacy 1
해부 DIEP → deep inferior epigastric perforator scispacy 1
해부 tissues scispacy 1
약물 titanium C0040302
titanium
scispacy 1
약물 beta-calcium pyrophosphate scispacy 1
약물 beta-tricalcium phosphate C0106141
beta-tricalcium phosphate
scispacy 1
약물 brushite compound scispacy 1
약물 beta-calcium scispacy 1
약물 brushite scispacy 1
질환 epithelioid sarcoma C0205944
Sarcoma, Epithelioid
scispacy 1
질환 osteomyelitis C0029443
Osteomyelitis
scispacy 1
질환 DIEP → deep inferior epigastric perforator scispacy 1
기타 bone flap scispacy 1
기타 Uppsala scispacy 1
기타 posterior scalp scispacy 1
기타 tissue expanders scispacy 1

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