The successful use of a bespoke OssDsign cranial plate to reconstruct an occipital defect following excision of a recurrent epithelioid sarcoma.
Abstract
A cranioplasty has a number of known associated complications including infection for non-biological implants and bone flap resorption where autologous grafts are used. In recent years, bioactive ceramic cranial implants have been developed as a new reconstructive option. The OssDsign cranial plate (OssDsign AB, Uppsala, Sweden) was first introduced in 2010 and consists of an interconnected mosaic of hydroxyapatite tiles mounted onto a 3D-printed titanium mesh. Each tile is composed of a monetite, beta-calcium pyrophosphate, beta-tricalcium phosphate and brushite compound designed to mimic the process of coupled bone formation once implanted. This case presents a patient's journey from diagnosis of an epithelioid sarcoma over the posterior scalp and its management in the following 7 years. Initial excision of the lesion was reconstructed with a tissue expander and local rotational flap. Recurrence of the disease 3 years later was treated with a course of radical radiotherapy. Persistent osteomyelitis over the next 3 years resulted in chronic ulceration and exposed bone in the treated area. As the first part of a 3-stage treatment plan, two separate tissue expanders became infected. The multidisciplinary team therefore chose to use a bespoke OssDsign cranial plate combined with a deep inferior epigastric perforator (DIEP) free flap to provide a definitive single operative solution. The advantages over other reconstruction options include that the plate can be removed should further excision be required, greater potential for long-term integration with surrounding tissues and the ability to be soaked in antibiotic to reduce the risk of infection.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | flap
|
피판재건술 | dict | 2 | |
| 합병증 | infection
|
감염 | dict | 2 | |
| 시술 | free flap
|
피판재건술 | dict | 1 | |
| 해부 | grafts
|
scispacy | 1 | ||
| 해부 | bone
|
scispacy | 1 | ||
| 해부 | tissue
|
scispacy | 1 | ||
| 해부 | DIEP
→ deep inferior epigastric perforator
|
scispacy | 1 | ||
| 해부 | tissues
|
scispacy | 1 | ||
| 약물 | titanium
|
C0040302
titanium
|
scispacy | 1 | |
| 약물 | beta-calcium pyrophosphate
|
scispacy | 1 | ||
| 약물 | beta-tricalcium phosphate
|
C0106141
beta-tricalcium phosphate
|
scispacy | 1 | |
| 약물 | brushite compound
|
scispacy | 1 | ||
| 약물 | beta-calcium
|
scispacy | 1 | ||
| 약물 | brushite
|
scispacy | 1 | ||
| 질환 | epithelioid sarcoma
|
C0205944
Sarcoma, Epithelioid
|
scispacy | 1 | |
| 질환 | osteomyelitis
|
C0029443
Osteomyelitis
|
scispacy | 1 | |
| 질환 | DIEP
→ deep inferior epigastric perforator
|
scispacy | 1 | ||
| 기타 | bone flap
|
scispacy | 1 | ||
| 기타 | Uppsala
|
scispacy | 1 | ||
| 기타 | posterior scalp
|
scispacy | 1 | ||
| 기타 | tissue expanders
|
scispacy | 1 |
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