Alternatives to Acellular Dermal Matrix: Utilization of a Gore DualMesh Sling as a Cost-Conscious Adjunct for Breast Reconstruction.

Eplasty 2017 Vol.17() p. e4

Grow JN, Butterworth J, Petty P

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Abstract

: This study seeks an alternative to acellular dermal matrix in 2-staged breast reconstruction while minimizing cost. It was hypothesized that use of a Gore DualMesh would allow for similar intraoperative tissue expander fill volumes, time to second-stage reconstruction, and number of postoperative fills compared with acellular dermal matrix at only a fraction of the expense. Retrospective analysis comparing Gore DualMesh (59 breasts, 34 patients), acellular dermal matrix (13 breasts, 8 patients), and total muscle coverage (25 breasts, 14 patients) for postmastectomy breast reconstruction was performed. Time to second-stage reconstruction, number of expansions, and relative initial fill volumes were compared between the 3 groups. Secondarily, complication rates were also considered, including seroma, infection, expander/implant explantation, removal of mesh, and capsular contracture. Statistical analysis was performed utilizing the Fisher exact test and the χ test for categorical variables and the Mann-Whitney test for continuous variables. Relative initial fill volumes, number of expansions, and time to second-stage reconstruction showed no statistical difference between the acellular dermal matrix and Gore DualMesh groups ( = .494, = .146, and = .539, respectively). Furthermore, the Gore DualMesh group underwent significantly fewer fills ( < .001) and had a higher relative initial fill volume ( < .001) than the total muscle coverage group. The additional cost per breast as a result of including DualMesh was on average $385 versus $4287 for acellular dermal matrix. Complication rates were similar between all 3 groups without statistically significant differences. Gore DualMesh represents a safe alternative to acellular dermal matrix for breast reconstruction with similar aesthetic results in certain patients at a fraction of the cost.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
재료 acellular dermal matrix 무세포진피기질 dict 7
해부 breast 유방 dict 5
해부 muscle scispacy 1
합병증 seroma 장액종 dict 1
합병증 infection 감염 dict 1
합병증 capsular contracture 피막구축 dict 1
질환 breasts scispacy 1
기타 tissue expander scispacy 1
기타 capsular scispacy 1

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