Alternatives to Acellular Dermal Matrix: Utilization of a Gore DualMesh Sling as a Cost-Conscious Adjunct for Breast Reconstruction.
Abstract
: This study seeks an alternative to acellular dermal matrix in 2-staged breast reconstruction while minimizing cost. It was hypothesized that use of a Gore DualMesh would allow for similar intraoperative tissue expander fill volumes, time to second-stage reconstruction, and number of postoperative fills compared with acellular dermal matrix at only a fraction of the expense. Retrospective analysis comparing Gore DualMesh (59 breasts, 34 patients), acellular dermal matrix (13 breasts, 8 patients), and total muscle coverage (25 breasts, 14 patients) for postmastectomy breast reconstruction was performed. Time to second-stage reconstruction, number of expansions, and relative initial fill volumes were compared between the 3 groups. Secondarily, complication rates were also considered, including seroma, infection, expander/implant explantation, removal of mesh, and capsular contracture. Statistical analysis was performed utilizing the Fisher exact test and the χ test for categorical variables and the Mann-Whitney test for continuous variables. Relative initial fill volumes, number of expansions, and time to second-stage reconstruction showed no statistical difference between the acellular dermal matrix and Gore DualMesh groups ( = .494, = .146, and = .539, respectively). Furthermore, the Gore DualMesh group underwent significantly fewer fills ( < .001) and had a higher relative initial fill volume ( < .001) than the total muscle coverage group. The additional cost per breast as a result of including DualMesh was on average $385 versus $4287 for acellular dermal matrix. Complication rates were similar between all 3 groups without statistically significant differences. Gore DualMesh represents a safe alternative to acellular dermal matrix for breast reconstruction with similar aesthetic results in certain patients at a fraction of the cost.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 재료 | acellular dermal matrix
|
무세포진피기질 | dict | 7 | |
| 해부 | breast
|
유방 | dict | 5 | |
| 해부 | muscle
|
scispacy | 1 | ||
| 합병증 | seroma
|
장액종 | dict | 1 | |
| 합병증 | infection
|
감염 | dict | 1 | |
| 합병증 | capsular contracture
|
피막구축 | dict | 1 | |
| 질환 | breasts
|
scispacy | 1 | ||
| 기타 | tissue expander
|
scispacy | 1 | ||
| 기타 | capsular
|
scispacy | 1 |
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