[Treatment of wrinkles with botulinum toxin].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2007 Vol.104(9) p. 777-82

Lanzl I, Merté RL

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Abstract

The use of botulinum toxin A for the treatment of wrinkles is increasing. Botulinum toxin A inhibits exocytosis of acetylcholine from 3 to 12 months, depending on the target tissue. Low-dose botulinum toxin A is used to smooth hyperkinetic facial lines. This is especially successful in the upper facial parts, since the target muscles (procerus, corrugator supracilii, frontalis, orbicularis oculi) all directly overlie the osseous structures of the face. This is not the case for the lower facial parts, and more side effects are encountered when treating, for example, wrinkles around the mouth. Contraindications to the use of botulinum toxin A are diseases affecting neuromuscular signal transduction, allergic reactions to components of the solution, therapy with aminoglycosides or acetylsalicylic acid prior to treatment, infections in the planned treatment area, and pregnancy and lactation. Alternative and complementary treatments include erbium-YAG or CO2 laser, as well as augmentation and surgical plastic procedures.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 botulinum toxin 보툴리눔독소 주사 dict 5
시술 co2 laser 레이저 박피술 dict 1
해부 smooth scispacy 1
해부 facial lines scispacy 1
해부 upper facial scispacy 1
해부 muscles scispacy 1
해부 procerus scispacy 1
해부 frontalis scispacy 1
해부 orbicularis oculi scispacy 1
해부 acetylcholine scispacy 1
해부 tissue scispacy 1
합병증 osseous structures scispacy 1
합병증 neuromuscular signal scispacy 1
합병증 wrinkles scispacy 1
약물 botulinum toxin A C0006050
botulinum toxin type A
scispacy 1
약물 acetylcholine C0001041
acetylcholine
scispacy 1
약물 Low-dose C1708745
Low-Dose Treatment
scispacy 1
약물 aminoglycosides C0002556
Aminoglycosides
scispacy 1
약물 acetylsalicylic acid C0004057
aspirin
scispacy 1
약물 CO2 C0007012
carbon dioxide
scispacy 1
약물 Low-dose botulinum toxin A scispacy 1
질환 hyperkinetic C0233574
Hyperkinetic
scispacy 1
질환 diseases affecting neuromuscular signal transduction, scispacy 1
질환 allergic reactions C0020517
Hypersensitivity
scispacy 1
질환 infections C0851162
Infections of musculoskeletal system
scispacy 1
질환 wrinkles scispacy 1
기타 corrugator scispacy 1
기타 botulinum toxin A scispacy 1

MeSH Terms

Adult; Animals; Botulinum Toxins, Type A; Combined Modality Therapy; Contraindications; Esthetics; Face; Facial Muscles; Female; Haplorhini; Humans; Injections, Intramuscular; Lactation; Laser Therapy; Lethal Dose 50; Middle Aged; Neuromuscular Agents; Posture; Pregnancy; Rhytidoplasty; Skin Aging; Surgery, Plastic; Time Factors; Treatment Outcome

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