Occurrence and activity of myofibroblasts in human capsular tissue surrounding mammary implants.
Abstract
Capsular tissue obtained from a series of 16 patients with silicone mammary implants was exposed in vitro to smooth-muscle stimulants and relaxants. Capsule relaxation was produced in 75 percent of the patients. The most active antagonists were papaverine and veratrine. Capsule contracture was produced in 69 percent of the patients. The most active agonists were histamine and epinephrine. Myofibroblasts were identified in several capsules. These data support the hypothesis that the myofibroblasts is a probable cause of capsular contracture.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 해부 | mammary
|
유방 | dict | 2 | |
| 해부 | myofibroblasts
|
scispacy | 1 | ||
| 해부 | Capsular tissue
|
scispacy | 1 | ||
| 해부 | smooth-muscle
|
scispacy | 1 | ||
| 해부 | capsular
|
scispacy | 1 | ||
| 합병증 | capsular contracture
|
피막구축 | dict | 1 | |
| 약물 | papaverine
|
C0030350
papaverine
|
scispacy | 1 | |
| 약물 | veratrine
|
C0042526
Veratrine
|
scispacy | 1 | |
| 약물 | histamine
|
C0019588
histamine
|
scispacy | 1 | |
| 약물 | epinephrine
|
에피네프린 | dict | 1 | |
| 질환 | silicone mammary implants
|
scispacy | 1 | ||
| 질환 | contracture
|
C0009917
Contracture
|
scispacy | 1 | |
| 질환 | Capsule
|
scispacy | 1 | ||
| 기타 | human capsular tissue surrounding mammary implants
|
scispacy | 1 | ||
| 기타 | patients
|
scispacy | 1 |
MeSH Terms
Adolescent; Adult; Breast; Connective Tissue; Contracture; Female; Fibroblasts; Humans; Middle Aged; Muscle Contraction; Postoperative Complications; Prostheses and Implants
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