When Benign Becomes Cancer: Malignant Degeneration of Chronic Inflammation.

Seminars in plastic surgery 2021 Vol.35(3) p. 159-163

Conlon C, Pupa L, Reece EM, Chu CK, Yu JZ, Vorstenbosch J, Winocour S

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Abstract

Chronic inflammation, long implicated in the genesis of malignancy, is now understood to underlie an estimated 25% of all cancers. The most pertinent malignancies, to the plastic surgeon, associated with the degeneration of chronic inflammation include Marjolin's ulcer, breast implant-associated large cell lymphoma, radiation-induced sarcoma, and Kaposi's sarcoma. The cellular and genetic damage incurred by a prolonged inflammatory reaction is controlled by an increasingly understood cytokinetic system. Advances in understanding the chronic inflammatory cascade have yielded new therapeutics and therapeutic targets.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 cellular scispacy 1
해부 breast 유방 dict 1
합병증 ulcer scispacy 1
질환 Cancer C0006826
Malignant Neoplasms
scispacy 1
질환 inflammation C0021368
Inflammation
scispacy 1
질환 malignancy C0006826
Malignant Neoplasms
scispacy 1
질환 cancers C0006826
Malignant Neoplasms
scispacy 1
질환 Marjolin's ulcer scispacy 1
질환 breast implant-associated scispacy 1
질환 sarcoma C1261473
Sarcoma
scispacy 1
질환 Kaposi's sarcoma C0036220
Kaposi Sarcoma
scispacy 1
질환 malignancies scispacy 1
질환 Marjolin scispacy 1
질환 breast implant-associated large cell lymphoma scispacy 1

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