[Revised version of the 4th edition of the WHO classification of malignant lymphomas : What is new?].

Der Pathologe 2019 Vol.40(2) p. 157-168

Ott G, Klapper W, Feller AC, Hansmann ML, Möller P, Stein H, Rosenwald A, Fend F

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Abstract

After 8 years, the WHO has now published the updated version of the 4th edition of the classification of hematopoietic and lymphoid tumors. This update provides a conceptual rewrite of existing entities as well as some new provisional entities and categories, particularly among the aggressive B‑cell lymphomas. Important new diagnostic categories include the high-grade B‑cell lymphomas, the large B‑cell lymphoma with IRF4 rearrangement, and the Burkitt-like lymphoma with 11q aberrations. Of particular importance, new concepts concerning the taxonomy and classification of early lymphoid lesions or precursor lesions are included, such as the in situ follicular neoplasia or the in situ mantle cell neoplasia. In addition, the concept of indolent lymphoproliferations, such as breast-implant-associated anaplastic large cell lymphoma and the indolent T‑cell lymphoproliferative disorder of the gastrointestinal tract, has been strengthened. Finally, diagnostic criteria for existing lymphoma entities have been refined.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 hematopoietic scispacy 1
해부 breast 유방 dict 1
합병증 lymphoid lesions scispacy 1
합병증 precursor lesions scispacy 1
합병증 anaplastic large cell lymphoma 보형물연관 역형성대세포림프종 dict 1
질환 malignant lymphomas C0024299
Lymphoma
scispacy 1
질환 aggressive B‑cell lymphomas scispacy 1
질환 high-grade B‑cell lymphomas scispacy 1
질환 Burkitt-like lymphoma C1368771
Burkitt-like lymphoma
scispacy 1
질환 lymphoid lesions scispacy 1
질환 neoplasia C0027651
Neoplasms
scispacy 1
질환 mantle cell neoplasia scispacy 1
질환 T‑cell lymphoproliferative disorder C0024314
Lymphoproliferative Disorders
scispacy 1
질환 lymphoma C0024299
Lymphoma
scispacy 1
질환 lymphoid tumors scispacy 1
질환 B‑cell lymphomas scispacy 1
질환 large B‑cell lymphoma scispacy 1
질환 follicular neoplasia scispacy 1
질환 indolent lymphoproliferations scispacy 1
질환 gastrointestinal tract scispacy 1
기타 IRF4 scispacy 1

MeSH Terms

Burkitt Lymphoma; Humans; Lymphoma; Lymphoma, B-Cell; Lymphoproliferative Disorders; World Health Organization

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