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[BACKGROUND] A microfocused ultrasound system with visualization (MFU-V) is currently indicated for use as a noninvasive dermatological aesthetic treatment to lift the eyebrows, lax submental and neck tissue, and improve lines and wrinkles …

[BACKGROUND] The aging process is a complex interplay of intrinsic and extrinsic factors across multiple layers of the face. Accordingly, combining aesthetic interventions targeting different manifestations of aging often leads to better re…

[BACKGROUND] The popularity of minimally invasive aesthetic procedures has increased globally, with a 40.9% increase in non-surgical procedures between 2019 and 2023. Dermal fillers have gained popularity for delivering visible results with…

[INTRODUCTION] Aging leads to facial volume loss, particularly in the forehead, resulting in a flat appearance and static wrinkles. Effective forehead rejuvenation aims to restore volume while minimizing risks associated with filler injecti…

[BACKGROUND] HA-CaHA is a hybrid injectable combining hyaluronic acid and calcium hydroxyapatite for dual-mode facial soft tissue augmentation. HA-CaHA-L includes 0.3% lidocaine HCL. [OBJECTIVE] This prospective, open-label study evaluated…

[PURPOSE] A combination of fillers and other modalities is often required to address all signs of periorbital aging. Patients are injected for volume loss, and for hyperpigmentation are treated with a combination treatments with chemical pe…

[BACKGROUND] Calcium hydroxyapatite (CaHA) fillers are widely used for soft-tissue augmentation due to their volumizing properties and biostimulatory effects. However, clinical evidence supporting the dual role of CaHA as both a volumizer a…

Calcium hydroxylapatite (CaHA) is widely used in aesthetics for its dual role as a dermal filler and biostimulator, promoting collagen and elastin synthesis. This study evaluates the comparative potential of CaHA in conventional saline dilu…

[BACKGROUND] Dermal fillers have been a popular choice for cosmetic dermatology procedures, and understanding the physical properties of microparticles used in dermal fillers is crucial for developing safe and effective aesthetic treatments…

[OBJECTIVES] The absorption of biostimulatory particulate matter following its application to fractional skin defects remains poorly understood, and even less is known about its in vivo impact in terms of tissue integration. The objectives …

Dermal fillers are among the most versatile tools in esthetic medicine. A broad range of temporary, semipermanent, and permanent filler products are on the market. We performed a narrative review on spontaneous and induced degradation of de…

[BACKGROUND] Calcium hydroxyapatite (CaHA) dermal filler has been increasingly used in facial aesthetic procedures. [OBJECTIVE] To investigate clinical and histological changes associated with calcium hydroxyapatite (CaHA) dermal filler in…

Filler-induced alopecia is a transient alopecia characterized by localized hair loss and often attributed to vascular compromise following dermal filler injections in facial regions. Although an uncommon phenomenon, the rising incidence of …

[BACKGROUND] Radiesse, a widely utilized calcium hydroxylapatite (CaHA) dermal filler, has shown effectiveness in soft tissue augmentation and regeneration. As with all dermal fillers, the potential for nodules may arise. Understanding the …

[BACKGROUND] Calcium hydroxylapatite (CaHA) dermal filler is used for a variety of aesthetic treatments; however, the safety and effectiveness of diluted CaHA for the treatment of décolleté wrinkles have not been established. …

[BACKGROUND] The perioral region plays a crucial role in facial aesthetics and is susceptible to age-related changes, such as wrinkles and fine lines due to its dynamic nature. Type I collagen is crucial in providing structural integrity an…

Radiesse is a dermal filler made of calcium hydroxylapatite, a natural component of the human body, which, in diluted and hyperdiluted forms, promotes, unlike other fillers, neocollagenesis, neoelastinogenesis, fibroblast proliferation, and…

[BACKGROUND] The aging process starts in the center of the face, in the periocular region and around the mouth, with a combination of volume loss, tissue descent, deepened wrinkles, and the loss of skin structure and quality. Recently, seve…

[INTRODUCTION] Calcium Hydroxylapatite (CaHA) is a common dermal filler used in aesthetic medicine for volumizing and contouring. Understanding mechanisms of actions of CaHA can help improve our understanding of its clinical applications. …