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The Role of the Microbiome in Pancreas Cancer: The Evolving Influence of the Fungal Mycobiome.
The gut microbiome has been shown to impact the progression of pancreatic ductal adenocarcinoma and the tumor's response to therapy. Microbial dysbiosis or changes in the healthy gut microbiome has been implicated in pancreatic cancer patie…
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Isolation and characterization of microbiota from human pancreatic tumors and small intestine.
Pancreatic ductal adenocarcinoma has a unique tumor microbiome and the systemic depletion of bacteria or fungi using antibiotic/antifungal cocktails leads to a decrease in pancreatic tumor burden in mice. However, functional studies remain …