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TNFAIP8L2 maintains hair cell function and regulates age-related hearing loss via mTORC1 signaling.
Age-related hearing loss (ARHL) is one of the most prevalent and complex disorders. Our previous study demonstrated that abnormal activation of mammalian target of rapamycin complex 1 (mTORC1) signaling in the cochlear neurosensory epitheli…
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Attenuated Angiogenesis and Macrophage Infiltration during Adipose Tissue Regeneration in Megavolume Human Fat Grafting.
[BACKGROUND] Survival and regeneration mechanisms of large (>250 mL) fat grafts remain incompletely understood. In fat grafts from volunteers with megavolume fat transfer breast augmentation, neovascularization and inflammatory cell infiltr…
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Development and validation of a predictive nomogram for vascular crises in oral and maxillofacial cancer patients undergoing free flap surgery.
[OBJECTIVE] To develop and validate a predictive model for identifying vascular crises following free tissue flap transplantation in patients undergoing surgery for oral and maxillofacial tumors. [METHODS] This retrospective cohort study u…
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Long-term outcomes of a new anatomy-based method for finding the medial cut end during late canalicular repair.
[BACKGROUND] Locating the medial cut end during late repair of canalicular lacerations can be challenging. [OBJECTIVE] The aim of this study was to evaluate the effectiveness and long-term outcomes of a new anatomy-based method for solving…
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Alternatively activated macrophages at the recipient site improve fat graft retention by promoting angiogenesis and adipogenesis.
The inflammatory response mediated by macrophages plays a role in tissue repair. Macrophages preferentially infiltrate the donor site and subsequently, infiltrate the recipient site after fat grafting. This study aimed to trace host-derived…