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8건 · 최신순-
Transoral laser microsurgery for glottic cancer: landmark 24-year single-institution experience with 661 patients and validation of the isoprognostic zone system.
[BACKGROUND] Transoral laser microsurgery (TOLMS) is a cornerstone organ-preserving treatment for early and selected intermediate glottic squamous cell carcinoma (LSCC). Prognostic value of infiltration patterns remains underexplored. We ev…
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Pre-Expanded Fronto-Scalp Flaps Combined With Botulinum Toxin and Laser Therapy for Secondary Large-Scale Craniofacial Defects.
[BACKGROUND] Secondary facial defects remain a primary focus in plastic surgery, particularly large defects involving the midface, forehead, and scalp. While tissue expansion of the fronto-scalp flap offers a viable reconstructive option, t…
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The real prognostic role of laryngeal dysplasia in patients affected by invasive cancer.
[PURPOSE] Transoral laser microsurgery is the mainstay in treating early-stage laryngeal squamous cell carcinoma. However, consensus is lacking in non-radical surgery for infiltrating cancer, and even doubts are cast for patients with laryn…
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Refining prognostic subcategories in intermediate-advanced glottic cancer: A multicentric study on 637 patients treated by transoral laser microsurgery.
[BACKGROUND] The current TNM staging system does not fully address the variations in glottic squamous cell carcinoma (SCC) extension and subsites involvement, especially if treated with transoral laser microsurgery (TOLMS). This study aims …
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Free-flap surgery with double innervation for smiling restoration in long standing facial paralysis: a literature review.
[PURPOSE] Currently, free-flap surgery with double innervation is considered a reliable and effective treatment in case of long standing facial paralysis. This study aimed to provide a current review of the literature (the "current state of…
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Unlocking tracheoesophageal speech from pharyngoesophageal spasm: preliminary results of a videofluoroscopic-guided botulinum toxin A injection technique.
[PURPOSE] The tracheoesophageal puncture for the voice prosthesis (VP) placement is the recognized gold standard in post-laryngectomy voice rehabilitation. Despite the development of specific intraoperative techniques, a subset of patients …
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Upfront transoral robotic surgery (TORS) intensity-modulated radiation therapy (IMRT) in HPV-positive oropharyngeal cancer: real-world data from a tertiary comprehensive cancer centre.
[OBJECTIVE] This study aims to provide real-world data on oncologic and functional outcomes of the most modern surgical and non-surgical treatments of locally advanced HPV-positive oropharyngeal cancer. [METHODS] We reviewed data on patien…
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Laryngeal dysplasia: Oncological outcomes in a large cohort of patients treated in a tertiary comprehensive cancer centre.
[PURPOSE] Laryngeal dysplasia represents a series of precancerous lesions, observed as laryngeal leukoplakia. General agreement has been lacking for their management and treatment ranging from simple biopsy to complete excision with cold bl…