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Histopathological Scoring Improves the Correlation Between Capsular Contracture Diagnosis and Patient-Reported Outcomes.
[BACKGROUND] The Baker classification is used to grade capsular contracture after breast-implant surgery; yet, its correlation with patient-reported outcomes is poor. [OBJECTIVES] To determine whether histopathological verification of caps…
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Breast Implant Rupture Is Strongly Associated with Capsular Contracture: An Intrapatient Study.
[BACKGROUND] Capsular contracture is a common complication following breast augmentation and reconstruction with implants. Implant rupture is suspected to cause capsular contracture, but the evidence remains limited. [METHODS] This intrapa…
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Quantifying Silicone Leakage In Vivo: Validation of a Reproducible Histological Method for Breast Implant Surveillance.
[BACKGROUND] Silicone leakage from breast implants may contribute to fibrosis leading to capsular contracture, yet no standardized method exists to quantify silicone leakage reliably. [OBJECTIVES] To validate a histological method for quan…
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Silicone Leakage From Breast Implants and Its Association With Capsular Contracture in 657 Patients.
[BACKGROUND] Capsular contracture is a common complication following breast reconstruction and augmentation, but there is limited evidence for the association between silicone leaking from the implant and capsular contracture. [OBJECTIVES]…
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Breast implant microbiome profile correlates with foreign body response severity.
Biomedical implants significantly enhance quality of life for millions of individuals worldwide. However, maintaining long-term implant function remains challenging, and it is often due to a severe foreign body response, characterized by fi…
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A Histological Assessment Tool for Breast Implant Capsules Validated in 480 Patients with and Without Capsular Contracture.
[BACKGROUND] Understanding the impact of breast implants on the histological response in the surrounding fibrous capsule is important; however, consensus is lacking on how to analyze implant capsules histologically. We aimed to develop a st…
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Long-Term Volume Retention of Breast Augmentation with Fat Grafting Depends on Weight Changes: A 3-Year Prospective Magnetic Resonance Imaging Study.
[BACKGROUND] Fat grafting is increasingly used for breast augmentation. However, long-term volume retention, time to reach steady state, and the effect of postoperative weight changes on these outcomes are not fully understood. [METHODS] I…
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Development and Validation of a Diagnostic Histopathological Scoring System for Capsular Contracture Based on 720 Breast Implant Capsules.
[BACKGROUND] Capsular contracture is traditionally evaluated with the Baker classification, but this has notable limitations regarding reproducibility and objectivity. [OBJECTIVES] The aim of this study was to develop and validate procedur…
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Factors Influencing Patient Satisfaction With Breast Augmentation: A BREAST-Q Effect of Magnitude Analysis.
[BACKGROUND] Breast augmentation is one of the most performed cosmetic surgeries. Despite this, patient satisfaction following breast augmentation is poorly understood. [OBJECTIVES] The aim of this study was to investigate what patient and…
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Hematoma and deep surgical site infection following primary breast augmentation: A retrospective review of 1128 patients.
[BACKGROUND] Breast augmentation is one of the most frequently performed cosmetic surgery worldwide. Some of the most severe short-term complications after breast augmentation are hematoma and deep surgical site infection. However, these co…
- Reply: Breast Augmentation with Microtextured Anatomical Implants in 653 Women: Indications and Risk of Rotation.
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Fat Grafting With Expanded Adipose-Derived Stromal Cells for Breast Augmentation: A Randomized Controlled Trial.
[BACKGROUND] The main challenge with fat grafting is loss of some of the graft to postsurgery resorption. Previous studies suggest that adipose-derived stromal cells (ASCs) can improve the volume retention of fat grafts but there is a lack …
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Deskinning in Inverted-T Mastopexy and Augmentation Mastopexy: A Retrospective Cohort Study.
[BACKGROUND] Most surgeons choose to de-epithelialize when performing a mastopexy to minimize the risk of nipple-areola-complex (NAC) necrosis. Preservation of the dermis and thus the subdermal plexus is thought to be crucial for the surviv…
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Breast Augmentation with Microtextured Anatomical Implants in 653 Women: Indications and Risk of Rotation.
[BACKGROUND] Anatomical implants provide a wide range of options in terms of implant dimensions for breast augmentation. Nevertheless, many surgeons choose not to use anatomical implants due to the risk of rotation malposition and because t…
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Breast Reduction with Deskinning of a Superomedial Pedicle: A Retrospective Cohort Study.
[BACKGROUND] In most breast reduction techniques, the pedicle of the nipple-areola complex (NAC) is de-epithelialized to preserve the subdermal plexus, thereby decreasing the risk of NAC necrosis. However, deskinning the pedicle is faster a…
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New Validated Method for Measuring Fat Graft Retention in the Breast with MRI.
In this study, we present a new method for measuring fat graft volume retention in the breast based on magnetic resonance imaging scans and a validation study to assess its accuracy and precision. The method was validated by 4 observers usi…
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The current gold standard breast volumetry technique seems to overestimate fat graft volume retention in the breast: A validation study.
[BACKGROUND] MRI is generally considered as the gold standard for measuring breast volume because of its high accuracy of the modality. Many techniques used to measure total breast volume have been validated, but none of these techniques ha…
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Avoiding a Systematic Error in Assessing Fat Graft Survival in the Breast with Repeated Magnetic Resonance Imaging.
Several techniques for measuring breast volume (BV) are based on examining the breast on magnetic resonance imaging. However, when techniques designed to measure total BV are used to quantify BV changes, for example, after fat grafting, a s…
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Delayed breast implant reconstruction: is radiation therapy associated with capsular contracture or reoperations?
We evaluated the association between radiation therapy and severe capsular contracture or reoperation after 717 delayed breast implant reconstruction procedures (288 1- and 429 2-stage procedures) identified in the prospective database of t…
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Importance of mesenchymal stem cells in autologous fat grafting: a systematic review of existing studies.
Autologous fat grafting (lipofilling) enables repair and augmentation of soft tissues and is increasingly used both in aesthetic and reconstructive surgery. Autologous fat has several advantages, including biocompatibility, versatility, nat…
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Delayed breast implant reconstruction: a 10-year prospective study.
Studies of complications following reconstructive surgery with implants among women with breast cancer are needed. As the, to our knowledge, first prospective long-term study we evaluated the occurrence of complications following delayed br…
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The clinical course of immediate breast implant reconstruction after breast cancer.
[BACKGROUND] The number of women suitable for breast conserving treatment as well as immediate reconstruction after breast cancer has been increasing, and studies of complications hereafter are needed. [MATERIAL AND METHODS] The cohort was…
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Long-term safety and effectiveness of style 410 highly cohesive silicone breast implants.
[BACKGROUND] In 2006, a single-center Swedish study demonstrated a low rupture rate and high patient satisfaction with the Style 410 shaped, form-stable gel implant. The current study aimed to validate the accuracy of the previously publish…
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Long-term outcome after mastectomy with immediate breast reconstruction.
[INTRODUCTION] The purpose of this study was to investigate long term outcome for women who had undergone mastectomy and immediate breast reconstruction. [MATERIAL AND METHODS] Patient files of 167 immediately reconstructed breast cancer p…