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How to define failure of intradetrusor injections of botulinum toxin A for neurogenic detrusor overactivity.
[INTRODUCTION] Neurogenic detrusor overactivity (NDO) has a major impact on patients' quality of life and can lead to upper urinary tract complications. Intradetrusor botulinum toxin type A injections are administered as second-line treatme…
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[Guidelines on the urological management of the adult patient with spinal dysraphism (spina bifida)].
[INTRODUCTION] Improved life expectancy and prenatal screening have changed the demographics of spina bifida (spinal dysraphism) which has presently become a disease of adulthood. Urinary disorders affect almost all patients with spinal dys…
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Efficacy and safety of intradetrusor botulinum toxin injections for idiopathic overactive bladder syndrome in patients with an artificial urinary sphincter.
[PURPOSE] To assess the efficacy and safety of intradetrusor botulinum toxin type A injections (IBTI) for idiopathic overactive bladder (iOAB) in non-neurological adults with an artificial urinary sphincter (AUS). [MATERIALS AND METHODS] W…
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Neurogenic bladder in patients with paraplegia: a two-center study of the real-life experience of the patients' journey.
[INTRODUCTION] Several patterns of urological dysfunctions have been described following spinal cord injury (SCI), depending on the level and the completeness of the injury. A better understanding of the natural history of neurogenic bladde…
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Urological dysfunction in patients with hereditary spastic paraplegia.
[AIMS] Purposes of this study were to describe lower urinary tract symptoms (LUTS) and related urodynamic patterns in patients with hereditary spastic paraplegia (HSP), and to characterize LUTS management and associated uronephrological com…
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Botulinum Toxin Type A Injection After Failure of Augmentation Enterocystoplasty Performed for Neurogenic Detrusor Overactivity: Preliminary Results of a Salvage Strategy. The ENTEROTOX Study.
[OBJECTIVE] To evaluate the clinical efficacy, urodynamic effect and safety of Botulinum Toxin A (BTXA) injections after failure of augmentation enterocystoplasty (AE) performed for neurogenic detrusor overactivity. [PATIENTS AND METHODS] …
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Urinary tract infections in patients with neurogenic bladder.
Urinary tract infections (UTIs) in patients with neurogenic bladder are a major public health issue due to their high incidence and major consequences. Despite their frequency and potential severity, their physiopathology and management are…
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Long-term outcomes and risks factors for failure of intradetrusor onabotulinumtoxin A injections for the treatment of refractory neurogenic detrusor overactivity.
[AIMS] Aims of this study were to assess the long-term outcomes of Intradetrusor injection of OnabotulinumtoxinA (Botox® injection) associated with clean intermittent-catheterization (CIC) for the treatment of neurogenic detrusor overactivi…
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Intradetrusor Injections of Botulinum Toxin A in Adults with Spinal Dysraphism.
[PURPOSE] The aim of the current study was to determine the outcomes of botulinum toxin A intradetrusor injections in adult patients with spina bifida. [MATERIALS AND METHODS] All patients with spinal dysraphism who underwent intradetrusor…
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Intradetrusor injection of botulinum toxin A and sacral neuromodulation for neurogenic detrusor overactivity.
Intradetrusor injection of botulinum toxin A and sacral neuromodulation are the two recommended third line treatments for patients with neurogenic detrusor overactivity, before undergoing with surgery. However, only Botox® injection is supp…
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Prospective evaluation of antibiotic treatment for urological procedure in patients presenting with neurogenic bladder.
[OBJECTIVES] Patients presenting with neurogenic bladder often require urological procedures (urodynamic testing and botulinum toxin injections) and a preventive antibiotic therapy. We aimed to assess the efficacy of this little known strat…
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[Definition of botulinum toxin failure in neurogenic detrusor overactivity: Preliminary results of the DETOX survey].
[OBJECTIVE] There is currently no guideline regarding the management of neurogenic detrusor overactivity (NDO) refractory to intra-detrusor botulinum toxin injections. The primary objective of the present study was to find a consensus defin…