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How to define failure of intradetrusor injections of botulinum toxin A for neurogenic detrusor overactivity.
[INTRODUCTION] Neurogenic detrusor overactivity (NDO) has a major impact on patients' quality of life and can lead to upper urinary tract complications. Intradetrusor botulinum toxin type A injections are administered as second-line treatme…
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Real-World Use of Intradetrusor Botulinum Toxin Injections: A Population-Based Study from France.
In recent decades, intradetrusor injections of botulinum toxin A (BoNT-A) have been widely applied to treat incontinence in both idiopathic overactive bladder (iOAB) and neurogenic detrusor overactivity incontinence (NDOI). This analysis, b…
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Determining the outcomes of urethral construction in phalloplasty.
[OBJECTIVE] To evaluate the surgical and functional outcomes of urethral reconstruction associated with phalloplasty, depending on the surgical techniques and patient history. [MATERIALS AND METHODS] We conducted a single-centre retrospect…
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[Guidelines on the urological management of the adult patient with spinal dysraphism (spina bifida)].
[INTRODUCTION] Improved life expectancy and prenatal screening have changed the demographics of spina bifida (spinal dysraphism) which has presently become a disease of adulthood. Urinary disorders affect almost all patients with spinal dys…
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Functional and surgical outcomes after phalloplasty in cis men.
[PURPOSE] Evaluate the surgical outcomes along with a comprehensive assessment of functional outcomes in cis men (non-trans) who underwent phalloplasty. [METHODS] All consecutive cis men who underwent phalloplasty from 2008 to 2018 for pen…
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Efficacy and safety of intradetrusor botulinum toxin injections for idiopathic overactive bladder syndrome in patients with an artificial urinary sphincter.
[PURPOSE] To assess the efficacy and safety of intradetrusor botulinum toxin type A injections (IBTI) for idiopathic overactive bladder (iOAB) in non-neurological adults with an artificial urinary sphincter (AUS). [MATERIALS AND METHODS] W…
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[Isolated continent urinary diversion: An interesting or often regretted indication?].
[INTRODUCTION] The aim of this study is to evaluate the percentage of patients developing vesical overactivity after the realization of a continent stoma without bladder enlargement. [MATERIAL AND METHOD] This is a retrospective monocentri…
- [Should we still offer botulinum toxin in first line treatment of idiopathic overactive bladder? Commentary to: Long-term follow-up reveals a low persistence rate of abobotulinumtoxinA injections for idiopathic overactive bladder].
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How long does the effect of botulinum toxin in neurogenic patients last? An analysis of the subset of "good responders".
[BACKGROUND] The aim of this study was to assess long-term efficacity of botulinum neurotoxin A (BoNT-A) in the treatment of neurogenic detrusor overactivity (NDO). [MATERIALS AND METHODS] This was a retrospective monocentric study in a re…
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[Long-term outcomes of intradetrusor botulinum toxin A in multiple sclerosis patients].
[INTRODUCTION] The objective of this study was to analyze the long-term efficiency and tolerance of TB in the management of anticholinergic refractory hyperactive bladder in patients with MS. [MATERIAL AND METHOD] Retrospective mono-centri…
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Botulinum Toxin Type A Injection After Failure of Augmentation Enterocystoplasty Performed for Neurogenic Detrusor Overactivity: Preliminary Results of a Salvage Strategy. The ENTEROTOX Study.
[OBJECTIVE] To evaluate the clinical efficacy, urodynamic effect and safety of Botulinum Toxin A (BTXA) injections after failure of augmentation enterocystoplasty (AE) performed for neurogenic detrusor overactivity. [PATIENTS AND METHODS] …
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Switch to Abobotulinum toxin A may be useful in the treatment of neurogenic detrusor overactivity when intradetrusor injections of Onabotulinum toxin A failed.
[AIMS] To assess the outcomes of switching to a different brand of botulinum toxin A (BTA, from Botox® to Dysport®) in case of failure of intradetrusor injections (IDI) of Botox® in the treatment of neurogenic detrusor overactivity (NDO). …
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[Patient information before bladder wall injection of botulinum toxin A (Botox): Which essential items? Results of Delphi consensus from GENULF experts].
[INTRODUCTION] Preoperative information before bladder wall injection of botulinum toxin A (Botox) holds several essential facts to understand and retain by the patients. The aim of this study was a review of essential preoperative informat…
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[Definition of botulinum toxin failure in neurogenic detrusor overactivity: Preliminary results of the DETOX survey].
[OBJECTIVE] There is currently no guideline regarding the management of neurogenic detrusor overactivity (NDO) refractory to intra-detrusor botulinum toxin injections. The primary objective of the present study was to find a consensus defin…