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Rational design and pairing of single-domain antibodies for developing rapid detection methods for botulinum neurotoxins A and B.
[BACKGROUND] Botulinum neurotoxin (BoNT) is a toxin produced by Clostridium botulinum that can cause neurological dysfunction in humans and animals, with BoNT/A and BoNT/B being responsible for the majority of poisoning cases. Due to its ex…
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Hypoxic cancer-associated fibroblast exosomal circSTAT3 drives triple negative breast cancer stemness via miR-671-5p/NOTCH1 signaling.
[BACKGROUND] The hypoxic tumor microenvironment, particularly hypoxia-conditioned cancer-associated fibroblasts (CAFs), drives breast cancer (BC) progression and therapy resistance. However, the molecular mechanisms linking hypoxic CAFs to …
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Fear of negative appearance evaluation and cosmetic surgery consideration among adolescents: A test of a moderated mediation model.
The surge in popularity of cosmetic surgery in recent years is noteworthy. In an era where societal standards of beauty increasingly shape individual development, it is imperative to comprehend the psychological factors that underpin the co…
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3D-printed microrobots for biomedical applications.
Microrobots, which can perform tasks in difficult-to-reach parts of the human body under their own or external power supply, are potential tools for biomedical applications, such as drug delivery, microsurgery, imaging and monitoring, tissu…
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Intraoperative salvaging of failure to harvest the bi-paddle anterolateral thigh flap: a case series.
[BACKGROUND] The size and versatility of anterolateral thigh (ALT) flap enables a bi-paddle flap to cover complex and extensive defects optimally. However, it is characterized by variations in the sources of blood vessels and in the number …
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The Tricky Diagnosis of Nummular Headaches: Description of Two Cases and Literature Review.
Nummular headaches are a rare and relatively newly characterized primary headache disorder. The epidemiology is largely unknown due to likely underdiagnosis and a small population of all headache patients in outpatient presentation. Though …
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Corrective Strategies for a Complex Deformity Caused by "European-Style Double Eyelid" Blepharoplasty in Asians.
[BACKGROUND] "European-style double eyelid" blepharoplasty often leads to a complex deformity, which includes one or more of the following features: a high fold, upper eyelid depression, multiple folds, an obvious scar, blepharoptosis, and …
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[ESTABLISHMENT AND TESTING OF RATING SCALE OF RAT ROTATOR CUFF FUNCTION].
[OBJECTIVE] To provides an objective tool to evaluate rotator cuff function in rats. [METHODS] Sixty adult male Sprague Dawley rats, weighing (281.21 ± 20.12) g, were involved in this experiment. Botulinum toxin A (6 U/kg) was injected int…