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Perioperative outcomes of robotic-assisted versus traditional surgery for DIEP flap breast reconstruction: a systematic review and meta-analysis.
[BACKGROUND] Breast cancer has the highest incidence among female malignancies, and surgical intervention remains a cornerstone of its management. However, destructive procedures such as traditional mastectomy or breast-conserving surgery c…
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Comparative Efficacy of Seroma Prevention Strategies in Abdominoplasty with Liposuction: A Systematic Review and Bayesian Model-based Network Meta-Analysis.
[BACKGROUND] Seroma is the most common complication after abdominoplasty, particularly when combined with liposuction. Multiple preventive strategies exist, but their relative effectiveness remains unclear. [OBJECTIVE] Using network meta-a…
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Hydrosurgical debridement system combined with negative pressure wound therapy for the treatment of large chronic wounds caused by polyacrylamide hydrogel injection for breast augmentation.
[BACKGROUND] Polyacrylamide hydrogel (PAHG) is a synthetic, gelatinous chemical substance commonly used as an injectable filler in breast augmentation surgery. However, its decomposition within several years postoperative often leads to var…
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Psychological Disorders Are a Non-negligible Factor in Medical Aesthetic Disputes.
[BACKGROUND] Psychological disorders play a crucial yet often overlooked role in medical aesthetic disputes. Patients with underlying psychological conditions may have unrealistic expectations, leading to dissatisfaction and legal conflicts…
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A web-based predictive model for secondary skin infections in breast cancer patients undergoing reconstruction.
[BACKGROUND] Breast cancer (BC) is one of the most common malignancies in women worldwide, with surgical interventions such as mastectomy and implant-based reconstruction playing a key role in management. While implant-based reconstruction …
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Expert consensus on apical microsurgery.
Apical microsurgery is accurate and minimally invasive, produces few complications, and has a success rate of more than 90%. However, due to the lack of awareness and understanding of apical microsurgery by dental general practitioners and …
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Hyaluronic Acid Injection Strategy of Infraorbital and Midfacial Rejuvenation for Women in Southeast China.
[BACKGROUND] The infraorbital and midfacial regions are critical aesthetic areas of concern for women. With aging, deformities such as tear troughs, eye bags, palpebromalar grooves, malar festoons, and nasolabial folds gradually appear. Hya…
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Reply to: Comment to: Hyaluronic Acid Injection Strategy of Infraorbital and Midfacial Rejuvenation for Women in Southeast China.
Tear trough correction poses unique challenges due to complex anatomy and ethnic variations. While immediate outcomes do not represent long-term efficacy, they are crucial for patient satisfaction in minimally invasive aesthetic procedures.…
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Nonhuman Primate Model of Super-selective Intra-arterial Ophthalmic Arterial Interventional Thrombolysis for Treatment of Ophthalmic Arterial Embolism Resulting From Hyaluronic Acid Filler Cosmetic Injection.
[BACKGROUND] Although intravascular interventional thrombolysis therapy is beneficial for patients suffering from impaired vision caused by hyaluronic acid (HA) embolism, there is no medical evidence-base for the efficacy of this treatment.…
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The Efficacy and Safety of Botulinum Toxin Type A in Prevention of Hypertrophic Scars After Epicanthoplasty: A Split-Face Double-Blinded Randomized Controlled Trial.
[BACKGROUND] Timely intervention can improve the aesthetic outcome of surgical scars, and botulinum toxin type A (BTXA) has demonstrated its potential as an effective treatment. However, conclusive scientific evidence is needed to definitiv…
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Rational design and pairing of single-domain antibodies for developing rapid detection methods for botulinum neurotoxins A and B.
[BACKGROUND] Botulinum neurotoxin (BoNT) is a toxin produced by Clostridium botulinum that can cause neurological dysfunction in humans and animals, with BoNT/A and BoNT/B being responsible for the majority of poisoning cases. Due to its ex…
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The effect and related mechanisms of RAC1 GTP on radiotherapy for hepatocellular carcinoma.
[BACKGROUND] Ras-related C3 botulinum toxin substrate 1 (), a pivotal Rho guanosine triphosphatases (GTPase) implicated in oncogenic processes and radiotherapeutic resistance across malignancies, has not been extensively examined within the…
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Foodborne Botulism Caused by Subtype A5(b3) by Self-Packaged Vacuum Spicy Rabbit Heads.
Botulism is a severe muscle paralysis disease mediated by the botulinum toxin. Here, we reported a foodborne botulism case caused by subtype A5(b3) from self-packaged vacuum spicy rabbit heads. Treatment for this case was delayed due to mi…
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Electroacupuncture combined with botulinum toxin type A promotes common peroneal nerve repair and activation of GDNF-BDNF/TrkB signaling pathway in post-stroke limb spasticity rats.
[BACKGROUND] Post-stroke limb spasticity (PSLS) is a rehabilitation problem that needs to be solved urgently, electroacupuncture (EA), a safe and effective adjunctive rehabilitation therapy with relatively few side effects, and botulinum to…
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Efficacy and Safety of Rb-bFGF in Hair Transplantation: A Prospective and Comparative Study.
[OBJECTIVE] This prospective randomized controlled trial aimed to evaluate the clinical value of recombinant bovine basic fibroblast growth factor (rb-bFGF)-based combined therapy in hair transplantation, focusing on its optimization effect…
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LL-MAROCO: A Large Language Model-Assisted Robotic System for Oral and Craniomaxillofacial Osteotomy.
Oral and craniomaxillofacial bone deformities necessitate treatment through osteotomy. Robot-assisted osteotomy appears promising in oral and craniomaxillofacial surgery, but it lacks sufficient intelligence and comprehensive integration of…
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Effectiveness, Complications, and Stability: A Long-term Retrospective Study of Himi-lengthening Genioplasty.
The authors conducted a retrospective analysis of the patients who underwent himi-lengthening genioplasty (HLG) in our department since 2020, using digital technology for a comprehensive comparative analysis of bone stability, facial symmet…
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A Randomized, Double-Blind, Placebo-Controlled, Multicentered Study to Evaluate the Efficacy and Safety of MEI005 in Reducing Submental Fat in Chinese Adults.
[BACKGROUND] Submental fat (SMF) is a common aesthetic concern traditionally treated with liposuction. Nonsurgical alternatives, like injectable deoxycholic acid, are gaining popularity. However, no related products have been clinically app…
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Complete Orbital Septum Release and Full Integration and Repositioning of Orbital Septal Fat Tissue (F.I.R.S.T.) in Transconjunctival Lower Blepharoplasty.
[BACKGROUND] After the introduction of orbital septal fat release and reposition in transconjunctival lower blepharoplasty (TCLB), few studies have addressed the thorough release of orbital fat tissue to adequately augment the tear trough a…
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Online selfie behavior and consideration of cosmetic surgery in teenage girls: The mediating roles of appearance comparisons and body dissatisfaction.
Although cosmetic surgery can repair functional impairments caused by deformities, improve appearance, and enhance self-esteem, it also carries certain risks, complications, and even death. To reduce the risks to life and property caused by…
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Exploring the Prevalence and Etiological Factors of Body Dysmorphic Disorder in Cosmetic Surgery Populations: Implications for Enhanced Clinical Assessment.
[BACKGROUND] The prevalence of body dysmorphic disorder (BDD) varies across different clinical settings, with evidence indicating its notable presence not only in psychiatric environments but also in dermatology and plastic surgery. This ar…
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The outcome of combined use of iRoot BP Plus and iRoot SP for root-end filling in endodontic microsurgery: a randomized controlled trial.
[OBJECTIVES] Root-end filling is important for the clinical outcome of endodontic microsurgery. Our previous study showed that combined application of iRoot BP Plus Root Repair Material (BP-RRM) and iRoot SP Injectable Root Canal Sealer (SP…
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Risk factors for postoperative late deterioration in patients with spinal dural arteriovenous fistulas.
[BACKGROUND] Approximately 86% of patients with spinal dural arteriovenous fistulas (SDVAFs) exhibit clinical improvement after surgery. However, 12%-55.8% of these patients experience late deterioration (LD) after an initial period of impr…
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Percutaneous Intra-arterial Hyaluronidase Injection for Hyaluronic Acid Filler Embolism Threatening Skin Barrier Integrity: Implementation of a Stepwise Treatment Protocol.
[BACKGROUND] Hyaluronic acid (HA) filler-induced vascular embolism that threatens skin integrity is an urgent situation. There is increasing evidence that percutaneous intra-arterial hyaluronidase injection is an effective therapeutic techn…
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Classification of gastrocnemius muscle hypertrophy for personalized botulinum toxin type A treatment.
[BACKGROUND] Owing to its safety and convenience, botulinum toxin type A (BoNtA) has become a first-choice treatment for contouring calf muscle asymmetries or deformities. Different injection methods and dosages have been discussed in the l…
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as a potential pan-cancer diagnostic, prognostic, and immunological biomarker.
[BACKGROUND] Ras-related C3 botulinum toxin substrate 1 () is an important member of the Rho GTPase family involved in tumorigenesis. However, its role and potential clinical utility across cancer entities in solid tumors is unknown. [METH…
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Subcutaneous infection caused by Mycobacterium abscessus following botulinum toxin injections: A case report and literature review.
[BACKGROUND] The rapid development of cosmetic injections has led to an increased incidence of nontuberculous mycobacterial (NTM) infection. [PATIENTS AND METHODS] Here, we presented a case of cutaneous Mycobacterium abscessus infection su…
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Dissecting and tracing the gut microbiota of infants with botulism: a cross sectional and longitudinal study.
[BACKGROUND] Infant botulism is caused by botulinum neurotoxin (BoNT), which is mainly produced by . However, there is a lack of longitudinal cohort studies on infant botulism. Herein, we have constructed a cross-sectional and longitudinal …
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The Effect of Calf Subcutaneous Fat Thickness on Patient Satisfaction after Calf Contouring with Botulinum Toxin A.
[BACKGROUND] As a minimally invasive therapy, botulinum toxin A (BTXA) treatment effectively reduces the hypertrophy of the gastrocnemius muscle (GM). Patient satisfaction is, however, reported to be low after treatment, with a possible cor…
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Madelung disease with postoperative priapism and multiple venous thromboses: case report and literature review.
Madelung disease is an uncommon metabolic disorder of uncertain pathogenesis, distinguished by the symmetric accumulation of nonencapsulated adipose tissue within the subcutaneous layer of the neck, abdomen, thighs, and other anatomical reg…