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11건 · 최신순-
Deep Phenotyping of Musicians' Upper Limb Dystonia.
[BACKGROUND] Focal task-specific dystonia of the musicians' arm (FTSDma) is an unusual and challenging disorder, often causing significant disability with loss of performing careers. The etiology and optimal management of this disorder rema…
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Incobotulinum Toxin-A in Professional Musicians with Focal Task-Specific Dystonia: A Double Blind, Placebo Controlled, Cross-Over Study.
[BACKGROUND] Musician's focal task-specific dystonia is a complex disorder of fine motor control, with incomplete understanding of its etiology. There have been relatively few trials of botulinum toxin in upper limb task-specific dystonia, …
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Comparison of Ultrasound and Electrical Stimulation Guidance for Onabotulinum Toxin-A Injections: A Randomized Crossover Study.
[BACKGROUND] Botulinum neurotoxin (BoNT) injection is an established therapy for limb spasticity and focal limb dystonia. Comparative benefits of injection guidance procedures have not been rigorously studied. [OBJECTIVES] We compared 2 ta…
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Twelve Drummers Drumming… With Dystonia.
[BACKGROUND] Reports of drummers' dystonia are rare, particularly compared to the literature on dystonia in string, piano and brass players. Several cases of drummers' dystonia have been included in large series of multiple instrumentalists…
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Transcranial magnetic stimulation therapy for focal leg dystonia: a case report.
[BACKGROUND] Dystonia is a debilitating disease that causes abnormal, often repetitive, movements, postures or both. The pathophysiology is unknown but related to loss of neuronal inhibition, aberrant sensorimotor integration, and/or derang…
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Phenomenology, genetics, and CNS network abnormalities in laryngeal dystonia: A 30-year experience.
[OBJECTIVE] Laryngeal dystonia (LD) is a functionally specific disorder of the afferent-efferent motor coordination system producing action-induced muscle contraction with a varied phenomenology. This report of long-term studies aims to rev…
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A novel therapeutic agent, sodium oxybate, improves dystonic symptoms via reduced network-wide activity.
Oral medications for the treatment of dystonia are not established. Currently, symptoms of focal dystonia are managed with botulinum toxin injections into the affected muscles. However, the injection effects are short-lived and not benefici…
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An open-label study of sodium oxybate in Spasmodic dysphonia.
[OBJECTIVES/HYPOTHESIS] Spasmodic dysphonia (SD) is a task-specific laryngeal dystonia that affects speech production. Co-occurring voice tremor (VT) often complicates the diagnosis and clinical management of SD. Treatment of SD and VT is l…
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The phenomenology and treatment of idiopathic adult-onset truncal dystonia: a retrospective review.
[BACKGROUND] Focal dystonia is the most common type of adult-onset dystonia; however, it infrequently affects truncal musculature. Although commonly attributed to secondary etiologies such as a neurodegenerative illness or tardive syndromes…
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Medical treatment of dystonia.
Therapeutic strategies in dystonia have evolved considerably in the past few decades. Three major treatment modalities include oral medications, botulinum toxin injections and surgical therapies, particularly deep brain stimulation. Althoug…
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Evaluating the musician with dystonia of the upper limb: a practical approach with video demonstration.
Focal task-specific dystonia is an unusual movement disorder that may affect musicians specifically when they perform on their instruments. Muscles of the lower face, lower limb and upper limb may be involved depending on the nature of the …