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MDS evidence-based review of treatments for essential tremor.
[BACKGROUND] Essential tremor is one of the most prevalent movement disorders. Many treatments for essential tremor have been reported in clinical practice, but it is uncertain which options have the most robust evidence. The International …
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Clinical Trial Designs and Measures in Hereditary Spastic Paraplegias.
Hereditary spastic paraplegias (HSPs) are a large group of genetically-diverse neurologic disorders characterized clinically by a common feature of lower extremity spasticity and gait difficulties. Current therapies are predominantly sympto…