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2건 · 최신순-
Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features.
[BACKGROUND] Increased understanding of the variability in normal breast biology will enable us to identify mechanisms of breast cancer initiation and the origin of different subtypes, and to better predict breast cancer risk. [METHODS] Ge…
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Expression of BMI-1 and Mel-18 in breast tissue--a diagnostic marker in patients with breast cancer.
[BACKGROUND] Polycomb Group (PcG) proteins are epigenetic silencers involved in maintaining cellular identity, and their deregulation can result in cancer. Expression of Mel-18 and Bmi-1 has been studied in tumor tissue, but not in adjacent…