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90건 · 최신순-
A Fibrous-Porous Microsphere-Based Composite Filler for Synchronized Immediate and Long-Term Soft Tissue Restoration.
Current injectable fillers often suffer from a transient efficacy and insufficient early stage improvement. To address this, we developed a composite dermal filler consisting of hyaluronic acid (HA) and poly-L-lactic acid-methoxypolyethylen…
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Safety and Efficacy of Recombinant Botulinum Toxin Type A for Moderate-to-severe Glabellar Lines: A Multicenter Randomized Controlled Trial.
[BACKGROUND] YY001 (Retoxin ®), the first global recombinant botulinum toxin type A (rBoNT/A) tested in humans, contains a pure 150-kDa core neurotoxin identical to natural BoNT/A (nBoNT/A). This study aimed to evaluate the safety and preli…
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Adverse neurological events following botulinum toxin type A: A case series of post-injection seizures and paralysis.
Within the field of rehabilitation and aesthetic medicine, botulinum neurotoxin (BoNT), particularly type A (BoNT-A), has gained significant popularity for its unique muscle-relaxing properties including muscular spasticity and reducing wri…
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Twenty Years of Macromastia Research: A Comprehensive Analysis of Diagnostic Standardization, Surgical Technique Optimization, and Exploration of Molecular Mechanisms.
Macromastia, characterized by excessive breast tissue growth, causes physical symptoms, psychosocial distress, and diminished quality of life. Despite the effectiveness of reduction mammaplasty, progress remains limited by inconsistent diag…
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Single-Session High-Dose Hyaluronidase for Managing Periorbital Hyaluronic Acid Filler Complications.
[BACKGROUND] Periorbital complications from hyaluronic acid (HA) fillers are common due to the region's unique anatomy. Hyaluronidase is widely used for management, but dosing remains empirical with no standardized protocol. This study aime…
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Fat Repositioning with Deep Fat Excision in Transcutaneous Lower Blepharoplasty.
[BACKGROUND] Lower blepharoplasty has shifted from fat resection to preservation by means of repositioning, yet severe fat herniation still requires selective excision. Traditional resection may compromise transposition. This study introduc…
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Biomechanical assessment in virtual surgical planning for mandibular reconstruction.
The fibula free flap has been widely used for reconstructing large segmental bone defects in the maxillofacial region. While mandibular reconstruction requires a high degree of precision, the impact of surgical deviations on clinical outcom…
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Risk Factors for Venous Thromboembolism Following Oral and Maxillofacial Cancer Surgery With Free Flap Reconstruction.
[BACKGROUND] Patients with oral maxillofacial cancer who undergo tumor resection and simultaneous free flap reconstruction face an increased risk of developing postoperative venous thromboembolism (VTE). However, the precise incidence, spec…
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The Assessment, Strategy, and Treatment Protocol: Nasolabial Fold Assessment, Strategy, and Treatment With Hyaluronic Acid Fillers in Chinese Patients.
[BACKGROUND] Causes contributing to nasolabial fold (NLF) appearance can be multifactorial, hence requiring distinct dermal filler strategies. We devised 4 assessment, strategy, and treatment (AST) injection protocols, incorporating NLF eti…
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VYC-25L Is Safe and Effective for Enhancing the Chin and Jawline by Correcting Chin Retrusion in Chinese Adults.
[BACKGROUND] Individuals with chin retrusion may seek chin and lower jawline aesthetic enhancement. [OBJECTIVES] To evaluate VYC-25L (Juvéderm Volux XC; Allergan Aesthetics, an AbbVie company), a lidocaine-containing injectable hyaluronic …
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Comparative Evaluation of the Biodegradability and Biocompatibility of Agarose Gel and Hyaluronic Acid Filler.
[BACKGROUND] The clinical success of soft tissue fillers hinges on their biodegradability and biocompatibility. While agarose gel, a clinically available filler, shows versatility across injection sites, its degradation behavior and tissue …
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Effectiveness of Botulinum Toxin A Injection for Hemiplegic Shoulder Pain: A Meta-Analysis of Randomized Controlled Trials.
Hemiplegic shoulder pain (HSP) is a common post-stroke complication impairing function and quality of life. Botulinum toxin A (BTA), a neurotoxin that inhibits acetylcholine release and reduces spasticity, has been proposed for treating HSP…
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Atrophy Masseter Recovery by Electrical Stimulation Mediated M2-Like Macrophage Polarisation via JAK/PI3K/AKT Pathway.
[BACKGROUND] Atrophy of the masseter muscle can result in an aged facial appearance and diminished chewing function. Electrical stimulation (ES) is known for its ability to facilitate tissue healing and functional recovery, but its precise …
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Efficacy and Safety of Chin Augmentation Using MaiLi-E, a Lidocaine-Containing Cross-Linked Sodium Hyaluronate Gel.
[BACKGROUND] MaiLi-E is a lidocaine-containing cross-linked sodium hyaluronate gel for dermal filling. This prospective, multicenter, randomized, delayed-treatment controlled, evaluator-blinded clinical trial aims to evaluate the efficacy a…
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Percutaneous External Fixation of Redistributed Orbital Fat in Transcutaneous Lower Eyelid Blepharoplasty.
[BACKGROUND] Although percutaneous external fixation has gained popularity in transconjunctival blepharoplasty due to its simplicity and minimal incision, internal fixation remains the standard approach in transcutaneous blepharoplasty. [O…
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Reflections on Aging Series: Multiple Factors Influencing Lower Blepharoplasty Procedure Selection in an East Asian Population.
[BACKGROUND] The lower eyelid, because of its unique functional and anatomical characteristics, is highly susceptible to early signs of aging. There is overlap in the manifestation of age-specific senescent features across age groups, with …
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Three-dimensional morphometric analysis of alar asymmetry in unilateral secondary cleft nasal deformity: implications for non-cleft alar reduction in surgical planning.
Preoperative surgical planning for alar reduction remains challenging due to the lack of objective references in traditional measurements. Therefore, this study aimed to objectively quantify preoperative bilateral alar symmetry using 3D bes…
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[Testis-sparing microsurgery for benign testis tumor: A report of 16 cases].
[OBJECTIVE] To investigate the safety and clinical effect of testis-sparing microsurgery (TSMS) in the treatment of benign testis tumor (BTT). [METHODS] We retrospectively analyzed the clinical data on 16 cases of BTT treated in the Depart…
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Intravesical injection of botulinum toxin type a may be an effective treatment option for autonomic dysreflexia in patients with high-level spinal cord injury.
[OBJECTIVE] To evaluate the efficacy of intravesical injection of botulinum toxin type A (BTX-A) for neurogenic detrusor overactivity (DO) in reducing the frequency and severity of autonomic dysreflexia (AD). [DESIGN] A cross-sectional non…
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Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting circ_0135062/miR-506-3p/Bax Axis.
Botulinum toxin type A (BTXA) has the potential to treat androgenetic alopecia (AGA); however, its impact on the apoptosis of dermal papillary cells (DPCs) is not yet fully understood. Noncoding RNAs play a crucial role in AGA. In this stud…
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DaxibotulinumtoxinA for injection to treat moderate or severe glabellar lines: A randomized, multicenter, Phase III, double-blind, placebo-controlled trial in China.
[BACKGROUND] DaxibotulinumtoxinA for injection (DAXI), a novel botulinum toxin type A formulation, is FDA-approved for glabellar lines treatment. Its clinical efficacy has been demonstrated in two Phase III trials (SAKURA 1 and SAKURA 2). …
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Therapeutic efficacy and safety of botulinum toxin A injection in plantar fasciitis: A systematic review and meta-analysis.
[OBJECTIVE] The purpose of this meta-analysis was to evaluate the therapeutic efficacy and safety of botulinum toxin A (BTA) injections for treatment of plantar fasciitis (PF). [METHODS] This review adhered to the PRISMA guidelines, conduc…
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Chin Augmentation and Treatment of Chin Retrusion with a Flexible Hyaluronic Acid Filler in Asian Subjects: A Randomized, Controlled, Evaluator-Blinded Study.
[BACKGROUND] Aesthetic improvement of the chin is increasingly requested by patients, including those of Chinese origin. [METHODS] A randomized, evaluator-blinded, no-treatment controlled study evaluated the effectiveness and safety of a f…
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Treatment of Chin Retrusion With Botulinum Toxin Plus Hyaluronic Acid Filler in Comparison With Hyaluronic Acid Filler Alone: A Randomized, Evaluator-Blinded, Controlled Study.
[BACKGROUND] Hyaluronic acid (HA) has already been widely administered for chin augmentation. Patients with chin retrusion frequently present with increased chin hypertonia. Monotherapy with HA falls short in addressing the multifaceted cos…
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A Novel Conchal Cartilage Harvesting Technique.
[BACKGROUND] Conchal cartilage is generally favored in rhinoplasty with a satisfied aesthetic outcome. However, patients may suffer from postoperative donor auricle deformities. [OBJECTIVES] This study introduced a novel conchal cartilage …
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Application and exploration of interprofessional education in the teaching of plastic and reconstructive surgery: a narrative review.
The growing discussion on "interdisciplinary integration" brings attention to the "interprofessional education" (IPE) in the field of plastic surgery. IPE not only improves the precision and effectiveness of plastic and reconstructive surge…
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Intraarterial Thrombolytic Treatment for Visual Deficits Caused by Hyaluronic Acid Filler: Efficacy, Safety, and Prognostic Factors.
[BACKGROUND] The benefits of intraarterial thrombolytic treatment (IATT) in reversing hyaluronic acid (HA)-related visual deficits remain unclear. This study aimed to report a 5-year experience in the treatment of visual deficits resulting …
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Effect of a New Hyaluronic Acid Hydrogel Dermal Filler Cross-Linked With Lysine Amino Acid for Skin Augmentation and Rejuvenation.
[BACKGROUND] Hyaluronic acid (HA) fillers are the most popular filler agents for skin rejuvenation. Although 1,4-butanediol diglycidyl ether is regarded as a relatively safe cross-linker, it still exhibits certain cytotoxicity. [OBJECTIVES…
- Botulinum toxin for Raynaud's phenomenon associated with systemic sclerosis: comment on the article by Senet et al.
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Botulinum Toxin Type A Injection for Correction of Upper Eyelid Retraction in Thyroid-Associated Ophthalmopathy.
Upper lid retraction (ULR) is the most common and earliest symptom in thyroid-associated ophthalmopathy (TAO) patients. Surgical correction is effective for ULR in stable diseases. However, non-invasive treatment is also required for the TA…