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Klotho inhibits renal ox-LDL deposition via IGF-1R/RAC1/OLR1 signaling to ameliorate podocyte injury in diabetic kidney disease.
[OBJECTIVE] Diabetic kidney disease (DKD) is characterized by the abnormal deposition of oxidized low-density lipoprotein (ox-LDL), which contributes to podocyte damage. Klotho, an aging suppressor that plays a critical role in protecting p…
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Reconstruction of the shortened columella in mild bifid nose using a propeller flap based on the nasal columella artery.
Bifid nose generally appears short columellar and lacks the nasal tip. Here, we describe a surgical correction technique for correcting the short columellar and nasal tip of bifid nose using a local flap to discuss outcomes, patient selectio…
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Trend of Academic Productivity in Plastic Surgery and the Impact of COVID-19: A Bibliometric Analysis.
[BACKGROUND] Plastic surgery has grown rapidly over the past decade, with increasing scientific output. The emergence of coronavirus disease 2019 (COVID-19) has a considerable impact on plastic surgery. [OBJECTIVE] To identify trends in pu…
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Bone remodeling following mandibular reconstruction using fibula free flap.
To investigate bone remodelling responses to mandibulectomy, a joint external and internal remodelling algorithm is developed here by incorporating patient-specific longitudinal data. The primary aim of this study is to simulate bone remode…
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Effects of varicocele and microsurgical varicocelectomy on the metabolites in semen.
The influence of varicocele and microsurgical varicocelectomy on semen quality remains unclear. Few studies have investigated the relationship between semen metabolism and the abnormalities in reproductive function caused by varicocele, how…
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On interaction between fatigue of reconstruction plate and time-dependent bone remodeling.
[BACKGROUND AND OBJECTIVE] The fibula free flap (FFF) has been extensively used to repair large segmental bone defects in the maxillofacial region. The reconstruction plate plays a key role in maintaining stability and load-sharing while th…
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"Dancing Coins?" Unexpected Finding During microsurgery and Potential Risk of Sperm Damage: Intrascrotal Calculi: A Retrospective Analysis.
[OBJECTIVE] Microsurgery of andrology always brings unexpected findings. Scrotal calculi are rare and unique, which are easily confused with tumor. To understand its etiology and harm, our study retrospectively analyzed the clinical charact…
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Juvéderm Volift (VYC-17.5L), a Hyaluronic Acid Filler with Lidocaine, is Safe and Effective for Correcting Nasolabial Folds in Chinese Subjects.
[PURPOSE] Hyaluronic acid injectable gels are commonly used to treat nasolabial folds (NLFs). We evaluated the safety and effectiveness of VYC-17.5L for correcting NLFs in Chinese subjects. [PATIENTS AND METHODS] This prospective, multicen…
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Efficacy and safety of hyaluronic acid fillers for lip augmentation in a Chinese population.
[BACKGROUND] Hyaluronic acid (HA) is an effective dermal filler for facial rejuvenation. This study aimed to observe the clinical efficacy of HA injection for lip augmentation in Chinese patients. [METHODS] From May 2019 to April 2020, 70 …
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A randomized, multicenter study on a flexible hyaluronic acid filler in treatment of moderate-to-severe nasolabial folds in a Chinese population.
[BACKGROUND] Restylane Defyne (HA , with lidocaine) has been shown to be effective and safe for facial augmentation including nasolabial folds (NLFs) in Caucasians. Incorporating lidocaine in injectable fillers has become a common practice …
- The combination of platelet-rich plasma with botulinum toxin A in the treatment of hyaluronic acid embolic cutaneous necrosis and alopecia.
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[Treatment of adult-acquired buried penis with suprapubic liposuction combined with modified Devine operation].
[OBJECTIVE] To evaluate the safety and efficacy of suprapubic liposuction combined with modified Devine surgery in adult patients with concealed penis caused by obesity. [METHODS] The clinical data of 26 adult patients with buried penis ad…
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Globe luxation may prevent myopia in a child: A case report.
[BACKGROUND] Globe luxation is rare and is mostly due to direct orbital trauma with fractures of the medial and floor walls, which displace the globe into the maxillary sinus. Only a few cases have been reported; moreover, patients who suff…
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Restylane Lyft for Aesthetic Shaping of the Nasal Dorsum and Radix: A Randomized, No-Treatment Control, Multicenter Study.
[BACKGROUND] Hyaluronic acid fillers are widely used in nonsurgical rhinoplasty. [METHODS] The authors performed a no-treatment control, multicenter, 12-month follow-up study to evaluate efficacy and safety of Restylane Lyft (Galderma, Upp…
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An Updated Definition of Plastic Surgery.
Modern medicine tends to provide comprehensive medical services based on disease or pathological features. As a result, the overlap between plastic surgery and other surgical departments greatly deepened. What was exclusively done by plasti…
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A modified crescent cartilage block for improving the retroauricular contour of the reconstructed ear: A retrospective cohort study.
[BACKGROUND] The use of a semilunar cartilage block to elevate a reconstructed ear does not always achieve a well-defined auriculocephalic sulcus. Herein, we modified the conventional crescent cartilage block through sculpting a concavity a…
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Medical Leadership: Experiences in the Use of Shared and Parental Leadership to Improve Academic Performance in the Management of a National Plastic Surgery Unit in China.
[BACKGROUND] Effective leadership is an integral component for optimal academic performance of surgical units. As one of the leading plastic surgery academic medical centers in China, the authors would like to share their experiences of usi…
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Fat Grafting for Facial Contouring (Temporal Region and Midface).
In this article the authors introduce a compartment-based fat graft for facial contouring, focusing on the anatomy of temporal region and midface, the 3L3M integrated fat transfer technique, and the facial compartment-based fat injection in…
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Suprapubic Liposuction With a Modified Devine's Technique for Buried Penis Release in Adults.
[BACKGROUND] With the increasing prevalence of overweight and obesity, adult-acquired buried penis is more common in recent years. Many surgical techniques have been reported. However, none is the gold standard. [OBJECTIVE] To evaluate the…
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Y-Shaped En-Bloc Mortise-Tenon Rhinoplasty Technique.
[BACKGROUND] Nasal tip management is the most important and challenging aspect of rhinoplasty. Costal cartilage can be utilized in septal extension grafting to effectively correct nasal shape deformity. [OBJECTIVES] The authors described t…
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Pseudo-allergic reaction caused by Qingkailing injection partially the PI3K-Rac1 signaling pathway in RBL-2H3 cells.
Qingkailing injection (QKLI) is a kind of multi-component traditional Chinese medicine injection. It has been widely used in clinical practice, but in recent years, it has caused more and more adverse reactions, mainly manifested as pseudo-…
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Early Postoperative Application of Botulinum Toxin Type A Prevents Hypertrophic Scarring after Epicanthoplasty: A Split-Face, Double-Blind, Randomized Trial.
[BACKGROUND] Postoperative hypertrophic scarring of the medial canthal area is a common phenomenon and deterrent for patients considering epicanthoplasty. Botulinum toxin type A has been reported for hypertrophic scar and keloid treatment. …
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Suspensory ligament release combined with acellular dermal matrix filler in infrapubic space: A new method for penile length augmentation.
Until now, no reliable method is recognised in treating buried penis. This study explored a new method of penile length augmentation using acellular dermal matrix filler in infrapubic space combined with liposuction and penile suspensory re…
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[Effect of human stromal vascular fraction gel on the treatment of patients with skin depressed scar and its mechanism].
To observe content of cytokine in human stromal vascular fraction gel (SVF-GEL) and effect of SVF-GEL on biological behaviors of epidermal and dermal cells in vitro and clinical efficacy of SVF-GEL. (1) SVF-GEL was prepared using liposucti…
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Modified Lower Blepharoplasty with Fat Repositioning via Transconjunctival Approach to Correct Tear Trough Deformity.
[BACKGROUND] Over the years, many techniques have been described to correct tear trough deformity (TTD). Fat-repositioning lower blepharoplasty via a transconjunctival approach is increasingly applied due to its satisfactory rejuvenating ef…
- Defining Plastic, Reconstructive, Aesthetic, and Cosmetic Surgeries: What Can Get Lost and Found in Translation.
- Reply: Facial Contouring by Targeted Restoration of Facial Fat Compartment Volume: The Midface.
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Long-term Outcomes of Temporal Hollowing Augmentation by Targeted Volume Restoration of Fat Compartments in Chinese Adults.
[IMPORTANCE] Previous anatomical and clinical studies have suggested that targeted restoration of the volume and distribution of fat compartments using appropriate cannula entry sites and injection planes is an excellent fat-grafting techni…
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OnabotulinumtoxinA treatment of moderate to severe glabellar lines in Chinese subjects after laser therapy: A prospective, open-label, noncomparative study.
[INTRODUCTION] This study evaluated safety and efficacy of onabotulinumtoxinA for moderate to severe glabellar lines (GL) following laser therapy in Chinese subjects. [MATERIALS AND METHODS] Subjects (n = 173) were followed for 120 days fo…
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Brain functional changes in patients with botulism after illegal cosmetic injections of botulinum toxin: A resting-state fMRI study.
[BACKGROUND] Botulinum toxin type A (BoNT-A) is generally considered safe and is widely used to treat a variety of clinical conditions involving muscle hyperactivity and for cosmetic purposes. However, the effects of BoNT-A poisoning (botul…