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29건 · 최신순-
Defining clinically significant tumor size in sporadic vestibular schwannoma to inform timing of radiosurgery during wait-and-scan management: further evidence supporting size threshold surveillance.
[OBJECTIVE] Wait-and-scan surveillance is now commonly employed for initial management of small- and medium-sized vestibular schwannomas. Although small differences in tumor size are unlikely to impact outcomes significantly, treatment with…
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Sex-based Differences in Quality of Life for Sporadic Vestibular Schwannoma Patients Managed With Observation, Microsurgery, or Radiation.
[OBJECTIVE] Quality of life (QOL) is an important consideration in vestibular schwannoma (VS) patients when assessing management options. Understanding sex-based differences in QOL may facilitate patient counseling. [STUDY DESIGN] Prospect…
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Salvage Microsurgery After Failed Bevacizumab Treatment for NF2-Related Schwannomatosis Vestibular Schwannoma: A Multicentric Retrospective Study.
[BACKGROUND AND OBJECTIVES] Surgery in NF2-related schwannomatosis (NF2-SWN) vestibular schwannoma (VS) carries a higher risk of facial nerve damage, hearing loss, and partial resection, than in sporadic cases. Radiosurgery is also associat…
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Management of vestibular schwannoma in the elderly.
The elderly population has been expanding and is expected to continue to do so in the future. This, together with advances in work-up for SNHL, led to an increase in the incidence of VS, with smaller tumor sizes and older ages at the time o…
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Optimal Timing of Primary Radiosurgical Treatment of Growing Vestibular Schwannoma: Insights From Salvage Microsurgery Outcomes.
[OBJECTIVE] Limited evidence guides the optimal timing of treatment after the detection of tumor growth during the observation of sporadic vestibular schwannoma (VS). The current work aimed to inform the timing of radiosurgical intervention…
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Prospective Symptom Changes in Sporadic Vestibular Schwannoma: A Comparison of Observation, Microsurgery, and Radiosurgery.
[OBJECTIVE] To compare differences in sporadic vestibular schwannoma (VS)-associated patient-reported symptom scores among patients receiving observation, microsurgery, or radiosurgery. [STUDY DESIGN] Prospective longitudinal survey. [SET…
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Trigeminal neuralgia pain outcomes following microsurgical resection versus stereotactic radiosurgery for petroclival meningiomas: a systematic review and meta-analysis.
[OBJECTIVE] Petroclival meningiomas (PCMs) are challenging lesions to treat because of their deep location and proximity to critical neurovascular structures. Patients with these lesions commonly present because of local mass effect. A symp…
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Salvage Microsurgery Following Failed Primary Radiosurgery in Sporadic Vestibular Schwannoma.
[IMPORTANCE] Management of sporadic vestibular schwannoma with radiosurgery is becoming increasingly common globally; however, limited data currently characterize patient outcomes in the setting of microsurgical salvage for radiosurgical fa…
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Repeat Radiosurgery for Sporadic Vestibular Schwannoma After Primary Radiosurgical Failure: An International Multi-institutional Investigation.
[OBJECTIVE] To describe outcomes of patients with sporadic vestibular schwannoma (VS) who underwent repeat stereotactic radiosurgery (SRS) after primary SRS failure. [STUDY DESIGN] Multi-institutional historical cohort study. [SETTING] Fi…
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Long-Term Prospective Quality-of-Life Outcomes in 445 Patients with Sporadic Vestibular Schwannoma.
[OBJECTIVE] To evaluate the long-term changes in sporadic vestibular schwannoma (VS) disease-specific quality-of-life (QOL) outcomes. [STUDY DESIGN] Prospective longitudinal study using the Penn Acoustic Neuroma Quality of Life (PANQOL) Sc…
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Comparing Patient Satisfaction After Upfront Treatment Versus Wait-and-Scan for Small Sporadic Vestibular Schwannoma.
[OBJECTIVE] Management of small vestibular schwannoma (VS) remains controversial, as patients are typically candidates for all three management options including microsurgery, stereotactic radiosurgery, or wait-and-scan. This study compares…
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Salvage radiosurgery following subtotal resection of vestibular schwannomas: does timing influence tumor control?
[OBJECTIVE] The goal of microsurgical resection of vestibular schwannoma (VS) is gross-total resection (GTR) to provide oncological cure. However, a popular strategy is to halt the resection if the surgical team feels the risk of cranial ne…
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Quality of Life in Sporadic Vestibular Schwannoma.
The focus of management in sporadic vestibular schwannoma has dramatically evolved over the last 100 years. The centrality of quality of life (QoL) is being underscored by an ongoing epidemiologic shift toward an older patient demographic t…
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Cochlear Implant Outcomes between Patients with Sporadic and Neurofibromatosis Type 2-Associated Vestibular Schwannoma.
[OBJECTIVE] Compare cochlear implant (CI) performance between patients with ipsilateral sporadic vestibular schwannoma (VS) and NF2-related schwannomatosis (NF2). Compare CI performance according to VS management modality. [STUDY DESIGN] H…
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Defining clinically significant tumor size in vestibular schwannoma to inform timing of microsurgery during wait-and-scan management: moving beyond minimum detectable growth.
[OBJECTIVE] Detection of vestibular schwannoma (VS) growth during observation leads to definitive treatment at most centers globally. Although ≥ 2 mm represents an established benchmark of tumor growth on serial MRI studies, 2 mm of linear …
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Long-term surgical outcomes of intracranial epidermoid tumors: impact of extent of resection on recurrence and functional outcomes in 63 patients.
[OBJECTIVE] The authors' objective was to reevaluate the role of microsurgery for epidermoid tumors by examining the associations between extent of resection (EOR), tumor control, and clinical outcomes. [METHODS] This was a retrospective s…
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Hearing Preservation Microsurgery in Vestibular Schwannomas: Worth Attempting in "Larger" Tumors?
[OBJECTIVES/HYPOTHESIS] To review hearing preservation after microsurgical resection of sporadic vestibular schwannomas according to tumor size. [STUDY DESIGN] Retrospective cohort. [METHODS] Baseline, intraoperative, and postoperative pa…
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Predicting Extent of Microsurgical Resection of Sporadic Vestibular Schwannoma.
[OBJECTIVE] Develop a predictive model for incomplete microsurgical resection of sporadic vestibular schwannoma (VS). [STUDY DESIGN] Historical cohort. [SETTING] Tertiary referral center. [PATIENTS] Patients with sporadic VS. [INTERVENT…
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Fluorescein-Assisted Microsurgical Resection of Vestibular Schwannoma: A Prospective Feasibility Study.
[OBJECTIVE] To evaluate the optimal dose and timing of administration of sodium fluorescein (SF) for selective fluorescence of sporadic vestibular schwannoma (VS) during microsurgery with the YELLOW 560-nm microscope filter (YE560) and to c…
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Prospective Study of Disease-Specific Quality-of-Life in Sporadic Vestibular Schwannoma Comparing Observation, Radiosurgery, and Microsurgery.
[BACKGROUND] Previous cross-sectional studies analyzing quality of life (QOL) outcomes in patients with sporadic vestibular schwannoma (VS) have shown surprisingly little difference among treatment modalities. To date, there is limited pros…
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Evolution in Management Trends of Sporadic Vestibular Schwannoma in the United States Over the Last Half-century.
[OBJECTIVE] Limited data currently characterize management trends of sporadic vestibular schwannoma (VS) in the United States over recent decades. Serving as the primary patient support organization in the United States, the Acoustic Neurom…
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Disease-Specific Quality of Life in Vestibular Schwannoma: A National Cross-sectional Study Comparing Microsurgery, Radiosurgery, and Observation.
[OBJECTIVE] To examine the impact of treatment on disease-specific health-related quality of life (HRQOL) among patients with sporadic vestibular schwannoma (VS). [STUDY DESIGN] National cross-sectional study. [SETTING] Tertiary referral …
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Long-term outcomes of grade I/II skull base chondrosarcoma: an insight into the role of surgery and upfront radiotherapy.
[PURPOSE] To clarify the need for post-operative radiation treatment in skull base chondrosarcomas (SBCs). [METHODS] A retrospective analysis of patients with grade I or II SBC. Patients were divided according to post-surgical treatment st…
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Surgery versus radiosurgery for facial nerve schwannoma: a systematic review and meta-analysis of facial nerve function, postoperative complications, and progression.
[OBJECTIVE] Intracranial facial nerve schwannomas (FNS) requiring treatment are frequently recommended for surgery or stereotactic radiosurgery (SRS). The objective of this study was to compare facial nerve function outcomes between these t…
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Large and small vestibular schwannomas: same, yet different tumors.
[BACKGROUND] Vestibular schwannomas (VS) present at variable size with heterogeneous symptomatology. Modern treatment paradigms for large VS include gross total resection, subtotal resection (STR) in combination with observation, and/or rad…
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Impact of Treatment on Vestibular Schwannoma-Associated Symptoms: A Prospective Study Comparing Treatment Modalities.
[OBJECTIVE] The degree to which various treatment modalities modify vestibular schwannoma (VS)-associated symptoms has received limited attention. The purpose of this study was to determine how different treatment modalities affect subjecti…
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Degree of preoperative hearing loss predicts time to early mobilization following vestibular schwannoma microsurgery.
[OBJECTIVE] To test the hypothesis that severe to profound preoperative hearing loss predicts less acute postoperative vestibulopathy following microsurgical removal of vestibular schwannoma (VS) allowing for earlier postoperative mobilizat…
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Surgical management for large vestibular schwannomas: a systematic review, meta-analysis, and consensus statement on behalf of the EANS skull base section.
[BACKGROUND AND OBJECTIVE] The optimal management of large vestibular schwannomas continues to be debated. We constituted a task force comprising the members of the EANS skull base committee along with international experts to derive recomm…
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Regional variation in vestibular schwannoma management and patient support group participation across the United States.
[PURPOSE] The Acoustic Neuroma Association (ANA) represents the largest existing patient support organization for those diagnosed with vestibular schwannoma (VS) in the United States. Yet, the degree to which the ANA is actually utilized ac…