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Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Hearing Preservation Outcomes in Patients With Sporadic Vestibular Schwannoma: Update.
[BACKGROUND] Given the increasing prevalence and shifting disease demographic of vestibular schwannoma toward smaller tumors in people with less advanced symptoms, increasing emphasis has been placed on functional hearing preservation. [OB…
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Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Surgical Resection for the Treatment of Patients With Vestibular Schwannomas: Update.
[BACKGROUND] Surgical intervention remains an important option in the management of vestibular schwannoma (VSs). Development of a systematic approach to choose the most appropriate route for this intervention, based on existing published ev…
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Defining clinically significant tumor size in sporadic vestibular schwannoma to inform timing of radiosurgery during wait-and-scan management: further evidence supporting size threshold surveillance.
[OBJECTIVE] Wait-and-scan surveillance is now commonly employed for initial management of small- and medium-sized vestibular schwannomas. Although small differences in tumor size are unlikely to impact outcomes significantly, treatment with…
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Microsurgical Obliteration of Craniocervical Junction Dural Arteriovenous Fistulas: Multicenter Experience.
[BACKGROUND] Dural arteriovenous fistulas (dAVFs) located at craniocervical junction are extremely rare (1%-2% of intracranial/spinal dAVFs). Their angio-architectural complexity renders endovascular embolization to be challenging given mul…
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Defining clinically significant tumor size in vestibular schwannoma to inform timing of microsurgery during wait-and-scan management: moving beyond minimum detectable growth.
[OBJECTIVE] Detection of vestibular schwannoma (VS) growth during observation leads to definitive treatment at most centers globally. Although ≥ 2 mm represents an established benchmark of tumor growth on serial MRI studies, 2 mm of linear …
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Long-term surgical outcomes of intracranial epidermoid tumors: impact of extent of resection on recurrence and functional outcomes in 63 patients.
[OBJECTIVE] The authors' objective was to reevaluate the role of microsurgery for epidermoid tumors by examining the associations between extent of resection (EOR), tumor control, and clinical outcomes. [METHODS] This was a retrospective s…
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Hearing Preservation Microsurgery in Vestibular Schwannomas: Worth Attempting in "Larger" Tumors?
[OBJECTIVES/HYPOTHESIS] To review hearing preservation after microsurgical resection of sporadic vestibular schwannomas according to tumor size. [STUDY DESIGN] Retrospective cohort. [METHODS] Baseline, intraoperative, and postoperative pa…
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Predicting Extent of Microsurgical Resection of Sporadic Vestibular Schwannoma.
[OBJECTIVE] Develop a predictive model for incomplete microsurgical resection of sporadic vestibular schwannoma (VS). [STUDY DESIGN] Historical cohort. [SETTING] Tertiary referral center. [PATIENTS] Patients with sporadic VS. [INTERVENT…
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Fluorescein-Assisted Microsurgical Resection of Vestibular Schwannoma: A Prospective Feasibility Study.
[OBJECTIVE] To evaluate the optimal dose and timing of administration of sodium fluorescein (SF) for selective fluorescence of sporadic vestibular schwannoma (VS) during microsurgery with the YELLOW 560-nm microscope filter (YE560) and to c…
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Prospective Study of Disease-Specific Quality-of-Life in Sporadic Vestibular Schwannoma Comparing Observation, Radiosurgery, and Microsurgery.
[BACKGROUND] Previous cross-sectional studies analyzing quality of life (QOL) outcomes in patients with sporadic vestibular schwannoma (VS) have shown surprisingly little difference among treatment modalities. To date, there is limited pros…
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Long-term outcomes of grade I/II skull base chondrosarcoma: an insight into the role of surgery and upfront radiotherapy.
[PURPOSE] To clarify the need for post-operative radiation treatment in skull base chondrosarcomas (SBCs). [METHODS] A retrospective analysis of patients with grade I or II SBC. Patients were divided according to post-surgical treatment st…
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Lifetime Cost and Quality-Adjusted Life-Years Across Management Options for Small- and Medium-Sized Sporadic Vestibular Schwannoma.
[OBJECTIVE] Despite the growing emphasis on healthcare costs, limited data address this aspect of care within the vestibular schwannoma (VS) literature. We sought to determine which strategy confers the lowest lifetime cost and greatest qua…
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Degree of preoperative hearing loss predicts time to early mobilization following vestibular schwannoma microsurgery.
[OBJECTIVE] To test the hypothesis that severe to profound preoperative hearing loss predicts less acute postoperative vestibulopathy following microsurgical removal of vestibular schwannoma (VS) allowing for earlier postoperative mobilizat…