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16건 · 최신순-
Calreticulin-driven immunogenic cell death promotes osteoclast differentiation and osteoarthritis progression via the LRP1/Rac1 signaling.
Aberrant osteoclast activation in subchondral bone is a hallmark of osteoarthritis (OA). This study identifies calreticulin (CALR), a key immunogenic cell death (ICD) marker, as a critical regulator of osteoclast differentiation and OA path…
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Serum RAC1 as a potential biomarker in the early stages of diabetic kidney disease.
[BACKGROUND] Preclinical studies have suggested that Ras-related C3 botulinum toxin substrate 1 (RAC1) accelerates diabetic kidney disease (DKD) progression by triggering renal inflammation/fibrosis. Nevertheless, the clinical relevance of …
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Multivariate analysis and nursing intervention strategies for intraoperative pressure ulcers in patients undergoing craniocerebral microsurgery.
[OBJECTIVE] This study aimed to investigate the various influencing factors for intraoperative pressure sores in patients with craniocerebral microsurgery and provide nursing intervention strategies for surgical pressure sores in a clinical…
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[Clinical effect of anterolateral thigh flow-through chimeric perforator free flap transplantation in the treatment of upper limb complex tissue defects with main artery injury].
To investigate the clinical effect of anterolateral thigh flow-through chimeric perforator free flap transplantation in the treatment of upper limb complex tissue defects with main artery injury. The study was a retrospective observational…
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Efficacy of type A botulinum toxin treatment for androgenetic alopecia using ultrasound combined with trichoscopy.
[OBJECTIVE] This study aimed to assess the efficacy of type A botulinum toxin treatment for androgenetic alopecia (AGA) using a combination of ultrasound and trichoscopy. [METHODS] Ninety patients with AGA who visited the Department of Der…
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A severe case of iatrogenic botulism associated with COVID-19 infection.
[BACKGROUND] The botulinum toxin is an extremely potent substance that impacts the nervous system. There has been a rise in cases of medical poisoning associated with it, particularly in the field of plastic and aesthetic procedures, in rec…
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Treatment of Facial Flaccidity and Sagging after Botulinum Toxin A Injection into the Masseter.
[BACKGROUND] Botulinum toxin A injection for masseter reduction is generally considered minimally invasive, safe, and effective. However, this approach may lead to facial flaccidity and sagging, especially in older patients with reduced ela…
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Is myasthenia gravis a contraindication for botulinum toxin?
Botulinum toxin (BTX) is a neurotoxin that has been used to treat various disorders and has also become a popular choice for cosmetic indications, yet traditionally, myasthenia gravis (MG) is considered a contraindication for BTX. To determ…
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Microsurgical Obstruction of Testes Fusion in Spodoptera litura.
Instead of using genetic methods like RNA interference (RNAi) and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated endonuclease Cas9, a physical barrier was microsurgically inserted between the testes of …
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Spinal hemangioblastoma: surgical procedures, outcomes and review of the literature.
[PURPOSE] total removal of spinal hemangioblastomas with satisfactory clinical outcomes remains a challenge. We aimed to evaluate the surgical outcomes of our spinal hemangioblastomas patients, summarize our experiences with this condition …
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Observation on the Curative Effect of Microsurgery in 154 Children with Strabismus and Analysis of Its Influencing Factors.
Strabismus is a common ophthalmic disease in the process of child body development, in which the two eyes cannot gaze at the target at the same time, and the incidence of this disease of children is higher. In children with esotropia, exotr…
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A mixed treatment comparison on efficacy and safety of treatments for spasticity caused by multiple sclerosis: a systematic review and network meta-analysis.
[OBJECTIVES] This study is aimed at providing a quantitative evaluation on different therapies of spasticity caused by multiple sclerosis. [DATA SOURCES] PubMed and Embase database. [REVIEW METHODS] We searched for randomized controlled t…
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Clinical Assessment of the Safety and Effectiveness of Nonablative Fractional Laser Combined with Transdermal Delivery of Botulinum Toxin A in Treating Periocular Wrinkles.
The upper and lower eyelids are traditionally contraindicated for subcutaneous botulinum toxin A (BTX) injection because of possible complications. We assessed the clinical safety and effectiveness of nonablative fractional laser (NAFL) com…
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Two Cases of Adverse Reactions of Hyaluronic Acid-based Filler Injections.
Hyaluronic acid (HA) is one of the natural components of the human body with high biocompatibility, biodegradability, and nonimmunogenicity, which makes it the ideal biomedical filling agent currently available. However, for many medical pr…
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[Different maxillomandibular advancement methods for the treatment of severe obstructive sleep apneahypopnea syndrome].
[OBJECTIVE] To review the outcomes of three different methods of maxillomandibular advancement for the treatment of severe obstructive sleep apnea-hypopnea syndrome (OSAHS). [METHODS] Twenty-four patients with severe OSAHS from January 201…
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A Comprehensive Strategy for Reconstruction of a Missing Midface.
The loss of midface structures always leads to significant functional and cosmetic deficits, and the reconstruction work remains a challenge for surgeons. We report a rare case with severe midfacial defects involving the maxilla, nasal bone…