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Efficacy and Safety of Novel Botulinum Toxin Type A (Protoxin) in the Treatment of Moderate to Severe Glabellar Lines: A Multicenter, Randomized, Double-Blind, Active-Controlled Phase III Study.
[BACKGROUND] A novel botulinum toxin type A (Protoxin; Protox Inc.) has been developed. [OBJECTIVE] To evaluate the efficacy and safety of the newly developed Protoxin compared to the approved drug onabotulinumtoxinA (OBoNT) in moderate to…
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A Phase 3, Randomized, Multi-center Clinical Trial to Evaluate the Efficacy and Safety of Neu-BoNT/A in Treatment of Primary Axillary Hyperhidrosis.
[BACKGROUND] Botulinum toxin type A is widely used to treat primary axillary hyperhidrosis and has proven to be an effective and safe approach. Onabotulinumtoxin A was approved by the FDA as a treatment for primary axillary hyperhidrosis. T…
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Efficacy and safety of neuronox for lateral canthal lines: a phase I/III, multicenter, randomized, double-blind, active-controlled study.
[INTRODUCTION] Neuronox has not yet been investigated for its efficacy and safety in the treatment of lateral canthal lines (LCL). [METHODS] This study was a randomized, double-blind, active drug controlled, multicenter, 16 week, Phase I/I…
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Efficacy and durability of hyaluronic acid fillers for malar enhancement: A prospective, randomized, split-face clinical controlled trial.
Various hyaluronic acid fillers can be used for facial attenuation and rejuvenation. The efficacy and durability of hyaluronic acid fillers are of major concern to dermatologists and patients. This study aimed to evaluate three-dimensional …
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Treatment of glabella skin necrosis following injection of hyaluronic acid filler using platelet-rich plasma.
Hyaluronic acid (HA) fillers have been widely used for soft-tissue augmentation. However, there can be various complications following HA filler injection. Skin necrosis is rare but one of the most disastrous side effects that, if not treat…
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Rejuvenation effects of hyaluronic acid injection on nasojugal groove: prospective randomized split face clinical controlled study.
[BACKGROUND] Pronounced nasojugal groove (tear trough deformity) is one of the landmarks of aging. Hyaluronic acid filler can be used for attenuating the nasojugal sulcus but irregular lumpness and overcorrection are common adverse reaction…