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217건 · 최신순-
Upregulation of miR-22 alleviates oxygen-glucose deprivation/reperfusion-induced injury by targeting Tiam1 in SH-SY5Y cells.
MicroRNA-22 (miR-22) has been reported to exert a neuroprotective effect. However, the specific role and mechanism of miR-22 in ischemia/reperfusion (I/R)-induced brain injury are still not known well. In this study, we evaluated whether mi…
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Calcium-sensing receptor protects intestinal integrity and alleviates the inflammatory response via the Rac1/PLCγ1 signaling pathway.
This study aimed to test the hypothesis that the calcium-sensing receptor (CaSR) can protect intestinal epithelial barrier integrity and decrease inflammatory response mediated by the Ras-related C3 botulinum toxin substrate 1 (Rac1)/phosph…
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Application of Autologous Hair Transplantation Technique in Children with Cicatricial Alopecia.
[INTRODUCTION] Cicatricial alopecia not only affects the appearance of children's heads and faces but also their mental health in the long term. This study aims to explore the therapeutic characteristics and clinical effects of autologous h…
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Cutis Laxa and the Value of Rhytidectomy: 4 Patients and Years of Follow-Up.
The modalities of the esthetic treatment of cutis laxa (CL) patients have rarely been discussed. Here, the authors present 4 CL rhytidectomy cases. The surgery method was designed based on the traditional full-incision face-lift technique c…
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Bipolar Radiofrequency-Assisted Liposuction for Cervical Contouring in Eastern Asians.
[BACKGROUND] East Asian beauty standards uphold a V-shaped face and a long slender neck. Some patients are dissatisfied with the concurrent nonsurgical treatment and prefer limited downtime with minimally invasive procedures to achieve a na…
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Application of subcutaneous radiofrequency after liposuction on midface: A minimally invasive technique for midface rejuvenation.
[BACKGROUND] Popular demand for minimally invasive soft tissue tightening is continuously on the rise. In recent years, subcutaneous radiofrequency or radiofrequency-assisted liposuction (RFAL) has been reported to produce the desired surgi…
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Engineering exosomes derived from subcutaneous fat MSCs specially promote cartilage repair as miR-199a-3p delivery vehicles in Osteoarthritis.
Osteoarthritis (OA) is a degenerative joint disease involving cartilage. Exosomes derived from Mesenchymal stem cells (MSCs) therapy improves articular cartilage repair, but subcutaneous fat (SC) stromal cells derived exosomes (MSCs-Exos), …
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Menstrual Phase and Menopausal Status Classification of Benign Breast Tissue Using Hormone-Regulated Gene Expression and Histomorphology: A Validation Study.
[BACKGROUND] The validation of breast cancer risk biomarkers in benign breast samples (BBS) is a long-sought goal, hampered by the fluctuation of gene and protein expression with menstrual phase (MP) and menopausal status (MS). Previously, …
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Safe Reproducible Breast Reduction.
Breast reduction is a common operation performed by plastic surgeons. Patients can have significant improvement in physical symptoms in addition to increased self-esteem, body image, and quality of life as a result. The authors describe com…
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What Can We Learn from Breast Implant Explantation: a 28-Year, Multicenter Retrospective Study of 1004 Explantation Cases.
[BACKGROUND] Implant-based breast augmentation remains popular, but the controversy over the safety and longevity of implants has continued. An event-based analysis of reasons for implant explantation may provide us with some insight into t…
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A modified Park's technique for creating a natural-looking double eyelid.
[OBJECTIVE] This study aimed to evaluate an improved park's technique to create a natural double eyelid and reduce scar formation. [METHODS] The levator aponeurosis, orbicularis oculi muscle, and dermis were fixed using subcutaneous interm…
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Misdiagnosis and Treatment of Corneal Complications Caused by Suture Exposure After Buried-Suture Double-Eyelid Blepharoplasty.
[PURPOSE] The purpose of this study was to summarize the misdiagnosis and treatment of corneal complications associated with suture exposure in cases of buried-suture double-eyelid blepharoplasty. [METHODS] This study retrospectively analy…
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A Modified Technique in Rhinoplasty: A Septal Extension Graft Complex Using Septal Cartilage, Ethmoid Bone, and Auricular Cartilage.
[BACKGROUND] Due to the small and weak septal cartilage of Asians, it is a challenge to obtain ideal tip projection and nose lengthening in this population by performing septal extension grafts with only septal cartilage. [OBJECTIVES] The …
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[Study on the influence of buried thread nasal augmentation on dorsal soft tissue of nose and revision rhinoplasty].
[OBJECTIVE] To investigate the influence of buried thread nasal augmentation on dorsal soft tissue of nose and revision rhinoplasty. [METHODS] A clinical data of 29 patients requesting revision rhinoplasty after buried thread nasal augment…
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Progranulin Promotes the Formation and Development of Capsules Caused by Silicone in Sprague-Dawley Rats.
[BACKGROUND] Silicone implants are currently the most widely used artificial materials in plastic surgery. Capsule formation following implant application is unavoidable. When the capsule is excessively thick and strongly contracted, it can…
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Engineered Customizable Microvessels for Progressive Vascularization in Large Regenerative Implants.
Inspired by the rapid angiogenesis of natural microvessels in vivo, engineered customizable microvessels (ECMVs) are developed which can naturally angiogenic sprout and induce vascular network formation via combing a celluar coaxial microfl…
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Microscopic Transsphenoidal Resection of Giant Pituitary Adenomas: Analysis of the Factors Limiting the Degree of Resection in 73 Cases.
[PURPOSE] To analyze the risk factors affecting the gross-total resection of giant pituitary adenomas using a transsphenoidal approach under a microscope to provide a reference basis for formulating an appropriate surgical strategy. [METHO…
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Prediction of postoperative recovery in patients with acoustic neuroma using machine learning and SMOTE-ENN techniques.
Acoustic neuroma is a common benign tumor that is frequently associated with postoperative complications such as facial nerve dysfunction, which greatly affects the physical and mental health of patients. In this paper, clinical data of pat…
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Impact of Transoral Radiofrequency Microsurgery and Radiotherapy on Long-term Swallowing Function in Patients with T1 Glottic Carcinoma.
To compare the impact of transoral radiofrequency microsurgery (TRM) and radiotherapy (RT) on long-term swallowing function in patients with T1 glottic carcinoma. A total of 41 cases of T1 glottic carcinoma treated with TRM or RT alone more…
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Imaging characteristics, misdiagnosis and microsurgical outcomes of patients with spinal dural arteriovenous fistula: a retrospective study of 32 patients.
[BACKGROUND] Spinal dural arteriovenous fistula (SDAVF) is an extremely rare spinal vascular malformation. As SDAVF exhibits no specific clinical manifestations nor diverse imaging results, it is easily misdiagnosed, resulting in delayed tr…
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Long-term outcomes of toe replantation: A review of ten cases.
[BACKGROUND] Foot injuries due to vehicular or other accidents are common. However, complete toe amputation is rare. This study explored the current protocols and clinical significance of toe replantation. [METHODS] From December 2011 to D…
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Hengli Chinese Botulinum Toxin Type A for Treatment of Patients With Overactive Bladder: A Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.
To evaluate the efficacy and safety of Hengli Chinese botulinum toxin type A (BTX-A; 100 U) in Chinese patients with overactive bladder. This study was a multicenter, randomized, double-blind, placebo-controlled trial in Chinese patients w…
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Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.
Avian hepatitis E virus (HEV) causes liver diseases and multiple extrahepatic disorders in chickens. However, the mechanisms involved in avian HEV entry remain elusive. Herein, we identified the RAS-related protein 1b (Rap1b) as a potential…
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Spermine protects intestinal barrier integrity through ras-related C3 botulinum toxin substrate 1/phospholipase C-γ1 signaling pathway in piglets.
Weaning stress can cause tight junctions damage and intestinal permeability enhancement, which leads to intestinal imbalance and growth retardation, thereby causing damage to piglet growth and development. Spermine can reduce stress. Howeve…
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Localization of the Center of the Intramuscular Nerve Dense Region of the Suboccipital Muscles: An Anatomical Study.
[PURPOSE] This study aimed to determine the body surface puncture position and depth of the center of the intramuscular nerve dense region in the suboccipital muscle to provide morphological guidance for accurate botulinum toxin A injection…
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Effects of Botulinum Toxin A on the Blood Flow in Expanded Rat Skin.
Poor blood supply can easily lead to expander extrusion and necrosis at the distal expanded flap. Botulinum toxin A (BTX-A) has been previously found to improve pedicled flap blood flow perfusion, but its effects on the blood supply of expa…
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Adaptation and Changes in Actin Dynamics and Cell Motility as Early Responses of Cultured Mammalian Cells to Altered Gravitational Vector.
Cultured mammalian cells have been shown to respond to microgravity (μG), but the molecular mechanism is still unknown. The study we report here is focused on molecular and cellular events that occur within a short period of time, which may…
- The combination of platelet-rich plasma with botulinum toxin A in the treatment of hyaluronic acid embolic cutaneous necrosis and alopecia.
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Botulinum toxin treatment for bielschowsky acquired commitant esotropia in adults.
[BACKGROUND] Many researchers have noticed that there is an increasing trend of Bielschowsky acquired comitant esotropia (ACE) in recent years related to excessive near work, but the exact pathogenesis and treatment methods have not been re…
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Low and high dose methamphetamine differentially regulate synaptic structural plasticity in cortex and hippocampus.
Psychostimulants, such as methamphetamine (METH) can induce structural remodeling of synapses by remodeling presynaptic and postsynaptic morphology. Escalating or long-lasting high dose METH accounts for neurodegeneration by targeting multi…