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257건 · 최신순-
A new surgical method of vasoepididymostomy for epididymal obstructive azoospermia to improve the success rate in the rat.
[BACKGROUND] Two-suture longitudinal intussusception vasoepididymostomy (LIVE) surgery has been confirmed by many studies in the treatment of epididymal obstruction; however, the success rate and anastomotic patency rate are not high, which…
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Robot-assisted augmented reality navigation for osteotomy and personalized guide-plate in mandibular reconstruction: a preclinical study.
[BACKGROUND] Oral and maxillofacial tumors, particularly those requiring mandibular reconstruction, present significant clinical challenges due to the complexities involved in achieving precise surgical outcomes and ensuring post-operative …
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Surgical outcomes in elderly patients with vestibular schwannoma: a retrospective cohort study.
This study aims to evaluate the surgical outcomes and clinical differences of elderly vestibular schwannoma (VS) patients (> 65 years), compared with non-elderly patients, focusing on baseline characteristics, preoperative symptoms, postope…
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The Efficacy of Half Purse Suture Technique in Eliminating "Dog-Ear" Deformity at Donor Site Incision in Deep Inferior Epigastric Perforator Flap (DIEP) Breast Reconstruction.
BackgroundTo evaluate the effectiveness of the half purse suture technique in eliminating the "dog-ear" deformity at the donor site incision of the Deep Inferior Epigastric Perforator flap (DIEP) for breast reconstruction.MethodFrom May to …
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Comparison of the Effects of Botulinum Toxin A Injection and Local Glucocorticoid Injection for Treating Laryngeal Contact Granuloma.
[OBJECTIVES] To compare the effects of botulinum toxin A injection and local glucocorticoid injection for treating laryngeal contact granuloma and to discuss the indications for both regimens. [METHODS] The case data of 50 patients with la…
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Botulinum toxin type A injections demonstrate remarkable efficacy in treating hemifacial spasm in elderly patients.
[OBJECTIVE] To investigate the effectiveness of botulinum toxin type A (BTX-A) injections in elderly patients with hemifacial spasm (HFS). [METHODS] In this retrospective study, a total of 120 elderly patients diagnosed with HFS were recru…
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Botulinum Toxin Type A for Nostril Overexposure: A Prospective Clinical Study Using 3D Scanning.
[BACKGROUND] Nostril overexposure is a common aesthetic concern among Asian populations, which significantly affects facial harmony. Traditional surgical interventions carry risks such as substantial trauma and visible scarring. This study …
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Disulfidptosis contributes to rotenone-induced dopaminergic neuron damage.
Parkinson's disease is a neurodegenerative disorder whose pathogenesis remains incompletely understood. Rotenone exposure is reportedly associated with Parkinson's disease. In addition, disulfidptosis is a newly identified form of cell deat…
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Botulinum Toxin A (BTA) for pain and function improvement in osteoarthritis: a systematic review and meta-analysis of clinical efficacy evidence from randomized controlled trials.
[OBJECTIVE] To evaluate the effectiveness of botulinum toxin A injections in improving pain and function in patients with osteoarthritis. [DESIGN] This study systematically searched the PubMed, Web of Science, Embase, Medline, Cochrane Lib…
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Nonmuscle-Mediated Effects of Botulinum Toxin A on Fat Graft Survival in Nude Mice: Timing-Dependent Graft Outcomes.
[BACKGROUND] Enhancing fat graft survival is a key goal in adipose regenerative medicine. Although botulinum toxin type A (BoNTA) has shown potential benefits, its effects beyond muscle paralysis remain incompletely understood. [OBJECTIVES…
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P21-activated kinase 4: a potent oncogene, molecular mechanisms and opportunities for targeted therapy.
[UNLABELLED] P21-activated kinase 4 (PAK4), recognized as a key effector protein of the Rho family of small G proteins Cell division regulatory protein 42 homologue (Cdc42) and Ras-related C3 botulinum toxin substrate 1 (Rac1), is a serine/…
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Case Report: fNIRS-guided rehabilitation in refractory post-traumatic dysphagia.
[BACKGROUND] Dysphagia is a common complication of severe traumatic brain injury (sTBI) and may persist despite standard treatment. For refractory cases, there appear to be no more effective therapeutic options available. [CASE INFORMATION…
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Trigger Point Injection: A Therapeutic Propellant for Myofascial Pain Syndromes.
Myofascial pain syndromes, stemming from trigger points within the muscles, represent a prevalent cause of localized or generalized pain in clinical practice. They have a high incidence rate and currently lack specific curative methods. Tri…
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Botulinum toxin therapy for neurological disorders: Serendipitous benefits on sleep quality and underlying mechanisms.
Botulinum toxin (BoNT) remains the gold standard treatment for focal and segmental dystonia and is widely used in managing hyperkinetic disorders, chronic pain, and glandular hypersecretion. Extensive clinical trials demonstrate that BoNT e…
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TIPE2 deficiency enhances macrophage phagocytosis of tumor cells.
[INTRODUCTION] Understanding the negative regulatory mechanisms of immune cell functions is essential for developing effective tumor immunotherapy strategies. Macrophages play a crucial role in antitumor immunity; however, the mechanisms th…
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Hair Transplantation on Free Flap in a Patient with Malignant Scalp Neoplasms: A Case Report.
This case report describes a pioneering approach to address severe alopecia following free flap reconstruction for malignant scalp tumor resection. A 41-year-old female with recurrent malignant fibrous histiocytoma underwent extensive scalp…
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Artificial intelligence in joint face-skeletal prediction for orthognathic procedures: A systematic review.
[OBJECTIVE] This systematic review aimed to produce an overview of the development of AI in joint skeletal-soft tissue prediction after orthognathic surgery, and to assess its accuracy comprehensively. [MATERIALS AND METHODS] Following PRI…
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Clinical Application of the High Superficial Musculoaponeurotic System for Facial Rejuvenation in Chinese Patients.
[BACKGROUND] Face lift surgery can improve facial sagging and reestablish a youthful relationship between the soft tissues and the underlying skeleton. The early manifestations of aging in the periorbital region include sagging of the later…
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A Randomized, Double-Blind, Placebo-Controlled, Multicentered Study to Evaluate the Efficacy and Safety of MEI005 in Reducing Submental Fat in Chinese Adults.
[BACKGROUND] Submental fat (SMF) is a common aesthetic concern traditionally treated with liposuction. Nonsurgical alternatives, like injectable deoxycholic acid, are gaining popularity. However, no related products have been clinically app…
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Subfascial Mini-Muscle Release Dual-Plane Technique: A Modified Procedure for Breast Augmentation.
[BACKGROUND] Each breast augmentation technique has advantages and indications, and the quest for the perfect implant pocket plane is ongoing. An ideal dual plane should meet 3 requirements: adequate implant coverage, optimal control of bre…
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Implications of Long-Term Double Eyelid Tape Use.
[BACKGROUNDS] The widespread adoption of double eyelid tapes (DET) to achieve the desired double eyelid aesthetic has prompted investigations into their long-term effects. Given the delicate and complex anatomy of the eyelid, concerns have …
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An Innovation Technique in East Asia Rhinoplasty.
[OBJECTIVE] To investigate the application and therapeutic efficacy of a novel cartilage framework: the external septa framework in East Asian rhinoplasty. [METHODS] From November 2021 to April 2023, Department of Plastic and Aesthetic (Bu…
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Application of scalp graft in the correction of severe alar retraction.
[BACKGROUND] Alar retraction is characterized by excessive nostril exposure and presents a significant challenge in rhinoplasty, particularly in cases of severe alar retraction. This study aimed to introduce a novel treatment approach for s…
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A retrospective study on different kind of cartilage frameworks on Asian rhinoplasty.
[BACKGROUND] The character of Asian nose usually presents low projection of tip, short columellar, and short nose, necessitating the construction of a cartilage framework to achieve optimal results. The objective of this study was to evalua…
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The application of external incision in correcting bulbous nasal tip caused by skin thickness in East Asian patients.
[BACKGROUND] Bulbous nasal tips in East Asian patients are often caused by thick skin and soft tissue hypertrophy, presenting challenges in rhinoplasty. This study evaluates the efficacy and safety of supratip excision combined with cartila…
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Revision Rhinoplasty After Non-Surgical Filler in East Asian Patients: A Safe and Effective Surgical Approach.
[INTRODUCTION] Recent advancements in non-surgical cosmetic technologies have increased their popularity for facial rejuvenation, particularly non-surgical rhinoplasty in the Asian region. However, variability in injection techniques, unkno…
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Multifactorial Subgroup Analysis of Surgical Strategy Selection for Different Types of Deviated Nose: A Comparative Study Based on Subjective and Objective Outcomes.
[BACKGROUND] Nasal deviation adversely impacts both airway function and facial aesthetics. The optimal surgical approach remains debated, particularly regarding how structural complexity modifies postoperative outcomes. [OBJECTIVES] The ai…
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Correction of Alar Retraction by Articulated Alar Rim Graft Combined with V-Y Advancement.
[BACKGROUND] The alar-columellar relationship was crucial for aesthetic evaluation of the lower nasal area, with alar retraction being a common and challenging deformity in Asian rhinoplasty. [OBJECTIVES] This study aims to evaluate the ef…
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L-Borneol promotes skin flap survival by regulating HIF-1α/NF-κB pathway.
[ETHNOPHARMACOLOGICAL RELEVANCE] The clinical application of skin flaps in surgical reconstruction is frequently impeded by the occurrence of distant necrosis. L-Borneol exhibits myogenic properties in traditional Chinese medicine and is us…
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Research progress on anatomy reconstruction of rat orthotopic liver transplantation.
Rat orthotopic liver transplantation (ROLT) serves as an ideal animal model and has gained popularity in addressing complications and perioperative treatments related to clinical liver transplantation. Through extensive research on ROLT mod…