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25건 · 최신순-
Fully endoscopic retrosigmoid keyhole approach versus traditional microscopic microsurgery for small-to-medium vestibular schwannomas: a retrospective matched-cohort study.
[BACKGROUND] The surgical management of vestibular schwannoma (VS) has shifted focus from mortality reduction to functional preservation and quality of life. While the traditional microscopic retrosigmoid approach is the gold standard, it s…
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An injectable photo-crosslinking silk hydrogel system with biphasic release of BTXA and 5-Fu promotes scarless wound healing.
Hypertrophic scarring is characterized by excessive dermal fibrosis and irregular collagen metabolism, mediated by fibroblasts derived from keloids. This condition typically arises from improper wound healing after deep burns, trauma, or su…
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Learning curve in mandibular reconstruction with vascularized iliac crest free flap: a cumulative sum analysis.
The repair of mandibular defects is challenging due to the functional and structural complexity of the mandible. The aim of this study was to evaluate the learning curve of mandibular reconstruction using a vascularized iliac crest free fla…
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Vascularized iliac crest free flap in maxillofacial reconstruction: Pearls and pitfalls from 437 clinical application.
[OBJECTIVE] The vascularized iliac crest free (VICF) flap has been a cornerstone in maxillofacial reconstruction for decades. This study aims to provide a framework for guiding and managing maxillofacial reconstruction using the VICF flap, …
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Deep Learning-Enhanced Robotic Subretinal Injection with Real-Time Retinal Motion Compensation.
Subretinal injection is a critical procedure for delivering therapeutic agents to treat retinal diseases such as inherited retinal diseases (IRD) and age-related macular degeneration (AMD). However, retinal motion caused by physiological fa…
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Iliac crest free flap versus fibula free flap for mandibular reconstruction: Cost-effectiveness analysis in a Chinese population.
Mandibular reconstruction is vital in oral and maxillofacial surgery to restore aesthetics and function after tumor resection or trauma. The iliac crest-free flap (ICFF) and fibula-free flap (FFF) are widely used, but their cost-effectivene…
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Vascularized iliac crest flap with double musculocutaneous skin islands for reconstruction of composite buccal and mandibular defects after gingival squamous cell carcinoma resection: A case report.
Mandibular gingival squamous cell carcinoma (GSCC) is a challenging malignancy often requiring extensive surgical resection and complex reconstruction. This study presents a 69-year-old male with left mandibular GSCC, treated with segmental…
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Atrophy Masseter Recovery by Electrical Stimulation Mediated M2-Like Macrophage Polarisation via JAK/PI3K/AKT Pathway.
[BACKGROUND] Atrophy of the masseter muscle can result in an aged facial appearance and diminished chewing function. Electrical stimulation (ES) is known for its ability to facilitate tissue healing and functional recovery, but its precise …
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Advances in etiology, pathophysiology, diagnosis, and management of lymphedema: a comprehensive review.
Lymphedema is a chronic disorder of impaired lymphatic transport that leads to fluid accumulation, fibrosis, and adipose expansion. It presents as primary disease, caused by genetic defects in lymphatic development, or as secondary disease …
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Electrical stimulation prevents condyle and subchondral degeneration following the masseter atrophy.
[OBJECTIVE] There is a strong relationship between masticatory muscle atrophy and condyle degeneration. Although electrical stimulation (ES) is an effective treatment for muscle atrophy, its influence on the underlying condyle is unclear. T…
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Does Linear or Spot Injection Technique Matter in Upper Face Botulinum Toxin Type A Application? A Split-Face Randomized Trial.
[BACKGROUND] Although the efficacy of botulinum toxin type A (BoNTA) has been shown to vary depending on injection layer, reconstitution volume, and BoNTA formulation, the effect of injection pattern has rarely been mentioned. The authors c…
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Botulinum toxin type A treatment of four cases of Wilson disease with lower limb dystonia: A prospective study.
Botulinum toxin type A (BoNT-A) has been recommended in various neurological disorders as a useful tool for alleviating dystonia. In Wilson disease (WD) patients with dystonia, BoNT-A injection can be used as a treatment modality when conve…
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Comparison of minimally-invasive fibular supporting of T-type with traditional bloody iliac flap metastasis for osteonecrosis of the femoral head at ARCO stage II.
[PURPOSE] Our research mainly evaluates the clinical efficacy of two surgical methods in the treatment of osteonecrosis of the femoral head (ONFH) at ARCO stage II, aiming to provide optimal hip-preserving treatment of ONFH. [METHOD] From …
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Comparison of Ultrasound and Electrical Stimulation Guidance for Onabotulinum Toxin-A Injections: A Randomized Crossover Study.
[BACKGROUND] Botulinum neurotoxin (BoNT) injection is an established therapy for limb spasticity and focal limb dystonia. Comparative benefits of injection guidance procedures have not been rigorously studied. [OBJECTIVES] We compared 2 ta…
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[Application of clip remodeling technique in microsurgical treatment of intracranial aneurysms via keyhole approaches].
To discuss the value and technique of clip remodeling in microsurgical treatment of intracranial aneurysms via keyhole approaches. The clinical data of patients with intracranial aneurysms, who were treated by microsurgical clipping via ke…
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Convection-enhanced delivery of botulinum toxin serotype A into the nonhuman primate cisterna magna and hippocampus.
[OBJECTIVE] Botulinum toxin serotype A (BoNT/A) was reported to raise the seizure threshold when injected into the seizure focus of a kindled rodent model. Delivering BoNT/A to the nonhuman primate (NHP) central nervous system via convectio…
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Botulinum toxin and occupational therapy for Writer's cramp.
[BACKGROUND] Writer's cramp (WC) is a form of focal hand dystonia, for which focal botulinum neurotoxin (BoNT) injections are the current best therapy. Past studies have shown that some types of rehabilitative therapy can be useful. We hypo…
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Clinical effectiveness of ultrasound guided subacromial-subdeltoid bursa injection of botulinum toxin type A in hemiplegic shoulder pain: A retrospective cohort study.
Hemiplegic shoulder pain (HSP), which occurs in most patients with hemiplegia, causes considerable distress and worsens outcomes in rehabilitation. Although they have received the treatments such as anti-inflammatory drugs or physical thera…
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Intra-articular injections of botulinum toxin a for refractory joint pain: a systematic review and meta-analysis.
[OBJECTIVE] To assess the benefit of intra-articular injection of Botulinum toxin A (BoNT-A) for chronic refractory joint pain regardless of joint or pathology. [DATA SOURCES] The search was performed on Ovid MEDLINE(R) In-Process and Othe…
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Efficacy and safety of botulinum toxin type A for upper limb spasticity after stroke or traumatic brain injury: a systematic review with meta-analysis and trial sequential analysis.
[INTRODUCTION] Muscle spasticity is a positive symptom after stroke and traumatic brain injury. Botulinum toxin type A (BoNT-A) injection is widely used for treating post stroke and traumatic brain injury spasticity. This study aimed to eva…
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Effectiveness of Botulinum Toxin for Lower Limbs Spasticity after Stroke: A Systematic Review and Meta-Analysis.
[OBJECTIVES] To evaluate current evidence of the effectiveness of botulinum toxin (BTX) injection for lower limbs spasticity after stroke. [METHODS] Ovid MEDLINE(R) In-Process and Other Non-Indexed Citations,Ovid MEDLINE(R), Ovid EMBASE, W…
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Differences in active range of motion measurements in the upper extremity of patients with writer's cramp compared with healthy controls.
[STUDY DESIGN] Exploratory case-control study. [INTRODUCTION] Writer's cramp (WC) is a type of focal hand dystonia. The central nervous system plays a role in its pathophysiology, but abnormalities in the affected musculoskeletal component…
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Soluble N-ethylmaleimide-sensitive Factor Attachment Receptor (SNARE) Protein Involved in the Remission of Depression by Acupuncture in Rats.
This study aims to investigate the molecular mechanisms of acupuncture in the remission of depression. A depressive disorder model was induced by exposing Sprague-Dawley rats to chronic unpredictable stress. The rats were divided into five …
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Effectiveness of Botulinum Toxin for Shoulder Pain Treatment: A Systematic Review and Meta-Analysis.
[OBJECTIVE] To evaluate the current evidence of the effectiveness of botulinum toxin (BTX) treatment for shoulder pain. [DATA SOURCES] Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE, Ovid EMBASE, Web of Science, and …
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Plastic surgery made easy - simple techniques for closing skin defects and improving cosmetic results.
[BACKGROUND] Although meticulous technique cannot guarantee a superior cosmetic result when repairing skin wounds or excising skin lesions, a well planned and executed repair reduces the risk of unsatisfactory scarring. [OBJECTIVE] This ar…