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34건 · 최신순-
Transoral laser microsurgery and open partial laryngectomy for limited-stage glottic cancer: a review of indications, oncologic and functional outcome, and prognosis.
For early-stage (T1-T2) glottic cancer, transoral laser microsurgery (TLM) and open partial laryngectomy (OPL) are primary organ-preserving options. This review compares their indications, outcomes, and prognostic factors based on a systema…
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A Multicenter, Randomized, Evaluator-Blind, No-Treatment Controlled Study of YVOIRE Y-Solution 720: A Volumizing Hyaluronic Acid Filler for Midface Volume Deficit.
[BACKGROUND] Midface volume deficiency is a common aesthetic concern that can be addressed with dermal fillers. YVOIRE Y-Solution 720 (YYS720) is a hyaluronic acid (HA)-based filler designed for midface augmentation. This study aimed to eva…
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Reconstructing through-and-through cheek defects using transposing cervicofacial and anterolateral thigh flaps-comparative analysis of aesthetic and functional outcomes.
Despite extensive efforts to restore through-and-through cheek defects caused by oral cavity malignancies, surgeons continue to explore optimal approaches to achieving satisfactory cosmetic and functional outcomes. In this prospective rando…
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Endoscopic surgery combined with titanium mesh for infantile solitary orbital myofibroma: a case report.
[BACKGROUND] To report the clinical features, misdiagnosis process and minimally invasive treatment experience of endoscopy combined with titanium mesh in a 3-year-old infant with isolated orbital myofibroma, and to discuss the key points o…
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Ultrasound-Guided "Cross Injection" Technique for Mouth Corner Lift with Botulinum Toxin Type A.
[BACKGROUND] Drooping mouth corner may lead to a sad, tired or aging appearance, which could be corrected by injection of botulinum neurotoxin. In the article, we describe a novel "cross injection" technique for mouth corner lift with botul…
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Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
[BACKGROUND] Microglia pyroptosis, a newly identified form of inflammatory cell death, is involved in the development of neuropathic pain (NP). Botulinum toxin type A (BTX-A) has been shown to be effective in relieving NP, but the mechanism…
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Enhancing Mid-Upper Facial Contours: Hairline Transplant Solutions for East Asian Women With High and Wide Foreheads.
[BACKGROUND] A high and wide forehead is a common congenital facial characteristic among East Asian women, often resulting in an imbalanced mid-upper facial proportion, diminished three-dimensional contour, and reduced femininity. Although …
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Enhancing Graft Survival Rates in Follicular Unit Excision: A Chinese Expert Consensus on Perioperative Procedures.
[BACKGROUND] The survival rate of grafts, a critical metric for evaluating the postoperative outcomes of follicular unit excision (FUE), can be significantly improved through standardized perioperative procedures. This expert consensus aims…
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Attenuated Angiogenesis and Macrophage Infiltration during Adipose Tissue Regeneration in Megavolume Human Fat Grafting.
[BACKGROUND] Survival and regeneration mechanisms of large (>250 mL) fat grafts remain incompletely understood. In fat grafts from volunteers with megavolume fat transfer breast augmentation, neovascularization and inflammatory cell infiltr…
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A novel simplified approach for endodontic retrograde surgery in short single-rooted teeth.
[BACKGROUND] High technical thresholds, long operative times, and the need for expensive and specialized equipment impede the widespread adoption of endodontic microsurgery in many developing countries. This study aimed to compare the effec…
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Research progress on anatomy reconstruction of rat orthotopic liver transplantation.
Rat orthotopic liver transplantation (ROLT) serves as an ideal animal model and has gained popularity in addressing complications and perioperative treatments related to clinical liver transplantation. Through extensive research on ROLT mod…
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:A retrospective study.
[BACKGROUND] It is widely acknowledged that botulinum toxin type A (BTX-A) has been widely used in the treatment of hemifacial spasm (HFS). However, there is currently a lack of systematic analysis of the factors affecting its therapeutic e…
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S-Nitrosylation of Septin2 Exacerbates Aortic Aneurysm and Dissection by Coupling the TIAM1-RAC1 Axis in Macrophages.
[BACKGROUND] S-Nitrosylation (SNO), a prototypic redox-based posttranslational modification, is involved in cardiovascular disease. Aortic aneurysm and dissection are high-risk cardiovascular diseases without an effective cure. The aim of t…
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Using Neuromodulators to Improve Scar Formation, Keloids, Rosacea, and Antiaging.
[BACKGROUND] Botulinum toxin A (BoNT-A) treatment has many uses in dermatology. Its mechanism of action and long-term effects for scar formation, rosacea, and antiaging are still being investigated. [OBJECTIVE] To conduct a literature revi…
- A novel method to clean hair follicular grafts in hair transplantation.
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A Comparative Study on the Application of Robotic Hair Restoration Technology Versus Traditional Follicular Unit Excision in Male Androgenetic Alopecia.
[BACKGROUND] The robotic hair transplant technology, ARTAS, has a series of fine mechanical structure and an intelligent recognition system that allows it to independently select hair follicular units (FUs) and effectively harvest hair. Aft…
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Chin Augmentation and Treatment of Chin Retrusion with a Flexible Hyaluronic Acid Filler in Asian Subjects: A Randomized, Controlled, Evaluator-Blinded Study.
[BACKGROUND] Aesthetic improvement of the chin is increasingly requested by patients, including those of Chinese origin. [METHODS] A randomized, evaluator-blinded, no-treatment controlled study evaluated the effectiveness and safety of a f…
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Intradermal Botulinum Toxin A on Skin Quality and Facial Rejuvenation: A Systematic Review and Meta-analysis.
[BACKGROUND] Botulinum toxin A (BTxA) has gained popularity as a nonsurgical aesthetic treatment for skin rejuvenation. However, previous studies on intradermal BTxA have shown inconsistent results. This systematic review and meta-analysis …
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Effect of botulinum toxin type A on non-motor symptoms and quality of life in Meige syndrome.
[BACKGROUND] It has been shown in previous studies that botulinum toxin type A (BTX-A) can effectively relieve the motor symptoms of Meige syndrome. However, its effect on non-motor symptoms (NMS) and quality of life (QoL) has not been comp…
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Microtoxin for Improving Pore Size, Skin Laxity, Sebum Control, and Scars: A Roundtable on Integrating Intradermal Botulinum Toxin Type A Microdoses Into Clinical Practice.
[BACKGROUND] In aesthetic clinical practice, botulinum toxin type A (BoNT-A) is best known for its use as a neuromodulator for the treatment of dynamic facial lines; however, when injected intradermally as microdroplets, BoNT-A can improve …
- Investigation of oral finasteride enhanced occipital hair diameter index in different types of male androgenetic alopecia.
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Deep tissue multi-photon imaging using adaptive optics with direct focus sensing and shaping.
High-resolution optical imaging deep in tissues is challenging because of optical aberrations and scattering of light caused by the complex structure of living matter. Here we present an adaptive optics three-photon microscope based on anal…
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A randomized, multicenter study on a flexible hyaluronic acid filler in treatment of moderate-to-severe nasolabial folds in a Chinese population.
[BACKGROUND] Restylane Defyne (HA , with lidocaine) has been shown to be effective and safe for facial augmentation including nasolabial folds (NLFs) in Caucasians. Incorporating lidocaine in injectable fillers has become a common practice …
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Botulinum toxin A (BoNT/A) for the treatment of depression: A randomized, double-blind, placebo, controlled trial in China.
[BACKGROUND] Depression is characterized by low moods, anhedonia, and social avoidance. Effective and acceptable treatments are required for depression. Positive effects on mood have been observed in patients with depression after treatment…
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The safety and efficacy of botulinum toxin A on the treatment of depression.
[OBJECTIVES] Effective strategy for the treatment of depression is limited. This study was to evaluate the safety and efficacy of botulinum toxin A (BoNT/A) in the treatment of depression. [METHODS] Seventy-six patients were assigned to th…
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Botulinum toxin type A promotes microglial M2 polarization and suppresses chronic constriction injury-induced neuropathic pain through the P2X7 receptor.
[BACKGROUND] Switching microglial polarization from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype represents a novel therapeutic strategy for neuropathic pain (NP). This study aims to investigate whether botulinum …
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Botulinum toxin type A alleviates neuropathic pain and suppresses inflammatory cytokines release from microglia by targeting TLR2/MyD88 and SNAP23.
[BACKGROUND] Botulinum toxin type A (BTX-A) was considered to be a new potential drug for neuropathic pain (NP) treatment. [RESULTS] In vivo, BTX-A attenuated chronic compression injury (CCI)-induced pain in rats, and reduced production of…
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Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer's disease.
Accelerated forgetting has been identified as a feature of Alzheimer's disease (AD), but the therapeutic efficacy of the manipulation of biological mechanisms of forgetting has not been assessed in AD animal models. Ras-related C3 botulinum…
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Onabotulinumtoxin A (BOTOX®) for ProphylaCTIC Treatment of Pediatric Migraine: A Retrospective Longitudinal Analysis.
[BACKGROUND] The use of onabotulinumtoxin A in the pediatric population has not been evaluated for chronic migraine in a longitudinal study. This retrospective study sought to determine the efficacy and safety of onabotulinumtoxin A in prop…
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Assessment of Functional Rhinoplasty with Spreader Grafting Using Acoustic Rhinomanometry and Validated Outcome Measurements.
[BACKGROUND] Rhinoplasty is 1 of the most common aesthetic and reconstructive plastic surgical procedures performed within the United States. Yet, data on functional reconstructive open and closed rhinoplasty procedures with or without spre…